The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase
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DOI: 10.3390/biom12010125
Abstract: Copper is essential for the stability and activity of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain. Copper is bound to COX1 and COX2, two core subunits of CcO, forming the… read more here.
Keywords: delivery pathway; copper; mitochondrial copper; cytochrome oxidase ... See more keywords
Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
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DOI: 10.7554/elife.64690
Abstract: The mitochondrial carrier family protein SLC25A3 transports both copper and phosphate in mammals, yet in Saccharomyces cerevisiae the transport of these substrates is partitioned across two paralogs: PIC2 and MIR1. To understand the ancestral state… read more here.
Keywords: transport; copper; copper phosphate; phosphate transporter ... See more keywords