Mitochondrial cristae remodelling is associated with disrupted OPA1 oligomerisation in the Huntington's disease R6/2 fragment model
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2016.10.017
Abstract: ABSTRACT There is evidence of an imbalance of mitochondrial fission and fusion in patients with Huntington's disease (HD) and HD animal models. Fission and fusion are important for mitochondrial homeostasis including mitochondrial DNA (mtDNA) maintenance… read more here.
Keywords: oligomerisation; mice; opa1 oligomerisation; fission fusion ... See more keywords
Vitamin D supplementation rescues simvastatin induced myopathy in mice via improving mitochondrial cristae shape.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115076
Abstract: Statin induced myopathy (SIM) is a main deleterious effect leading to the poor treatment compliance, while the preventive or therapeutic treatments are absent. Mounting evidences demonstrated that vitamin D plays a vital role in muscle… read more here.
Keywords: induced myopathy; supplementation; vitamin supplementation; mitochondrial cristae ... See more keywords
The Origin of Mitochondrial Cristae from Alphaproteobacteria
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msw298
Abstract: Mitochondria are the respiratory organelles of eukaryotes and their evolutionary history is deeply intertwined with that of eukaryotes. The compartmentalization of respiration in mitochondria occurs within cristae, whose evolutionary origin has remained unclear. Recent discoveries,… read more here.
Keywords: cristae; origin mitochondrial; biology; cristae alphaproteobacteria ... See more keywords
Severe COVID‐19 correlates with lower mitochondrial cristae density in PBMCs and greater sitting time in humans
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15369
Abstract: An interaction between mitochondrial dynamics, physical activity levels, and COVID‐19 severity has been previously hypothesized. However, this has not been tested. We aimed to compare mitochondrial morphology and cristae density of PBMCs between subjects with… read more here.
Keywords: time; density; severe covid; cristae ... See more keywords