Synthesis, Crystal Structures and Anti-lung Cancer Effects of Two Copper(II) Coordination Polymers Mediated by Mitochondrial-Dependent Apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-019-01129-9
Abstract: In this study, two new Cu(II)-based coordination polymers {[Cu2(pdc)2](DMF)2}n (1, H2pdc = pyridine-3,5-bis(phenyl-4-carboxylic) acid) and {[Cu2(ndc)2(bpee)2]2.5H2O}n (2, H2ndc = 1,2-naphthalenedicarboxylic acid, bpee = trans-1,2-bis(4-pyridyl)ethylene) have been successfully prepared under different solvothermal conditions. In addition, the anti-proliferation activity of compounds 1 and… read more here.
Keywords: coordination polymers; cell; mitochondrial dependent; lung cancer ... See more keywords
Evidence that PKCα inhibition in Dalton's Lymphoma cells augments cell cycle arrest and mitochondrial-dependent apoptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia research"
DOI: 10.1016/j.leukres.2021.106772
Abstract: Protein kinase Cα (PKCα), belonging to ser/thr protein kinase, perform various biological functions. Overexpression of PKCα has been observed in multiple human malignancies including lymphoma. However, the molecular pathogenesis and involvement of PKCα in Non-Hodgkin… read more here.
Keywords: dependent apoptosis; mitochondrial dependent; lymphoma; pkc inhibition ... See more keywords
Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/2479234
Abstract: Hexachloronaphthalene (PCN67) is one of the most toxic among polychlorinated naphthalenes. Despite the known high bioaccumulation and persistence of PCN67 in the environment, it is still unclear to what extent exposure to these substances may… read more here.
Keywords: reactive oxygen; oxygen species; neurotoxicity; pcn67 ... See more keywords