Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
Sign Up to like & getrecommendations! Published in 2022 at "Current Biology"
DOI: 10.1016/j.cub.2022.02.058
Abstract: Mitochondrial damage (MtD) represents a dramatic change in cellular homeostasis, necessitating metabolic changes and stimulating mitophagy. One rapid response to MtD is a rapid peri-mitochondrial actin polymerization termed ADA (acute damage-induced actin). The activation mechanism… read more here.
Keywords: mitochondrial depolarization; shape changes; depolarization; actin polymerization ... See more keywords
Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2046457
Abstract: ABSTRACT Ethanol increases hepatic mitophagy driven by unknown mechanisms. Type 1 mitophagy sequesters polarized mitochondria for nutrient recovery and cytoplasmic remodeling. In Type 2, mitochondrial depolarization (mtDepo) initiates mitophagy to remove the damaged organelles. Previously,… read more here.
Keywords: mitochondrial depolarization; treatment; ethanol treatment; gfp lc3 ... See more keywords
Hepatitis C virus p7 induces mitochondrial depolarization of isolated liver mitochondria.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.7809
Abstract: Hepatitis C virus (HCV)‑encoded protein p7 is a viroporin that acts as an ion channel and is indispensable for HCV particle production. Although the main target of HCV p7 is the endoplasmic reticulum, it also… read more here.
Keywords: mitochondrial depolarization; liver mitochondria; hcv; hepatitis virus ... See more keywords