Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy.
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DOI: 10.1161/circresaha.119.314681
Abstract: Anthracycline-based chemotherapy can result in the development of a cumulative and progressively developing cardiomyopathy. Doxorubicin is one of the most highly prescribed anthracyclines in the United States due to its broad spectrum of therapeutic efficacy.… read more here.
Keywords: doxorubicin induced; induced cardiomyopathy; doxorubicin; mitochondrial determinants ... See more keywords
Mitochondrial Determinants of Anti-Cancer Drug-Induced Cardiotoxicity
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DOI: 10.3390/biomedicines10030520
Abstract: Mitochondria are key organelles for the maintenance of myocardial tissue homeostasis, playing a pivotal role in adenosine triphosphate (ATP) production, calcium signaling, redox homeostasis, and thermogenesis, as well as in the regulation of crucial pathways… read more here.
Keywords: drug induced; determinants anti; induced cardiotoxicity; anti cancer ... See more keywords