Dexamethasone promotes mesenchymal stem cell apoptosis and inhibits osteogenesis by disrupting mitochondrial dynamics
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12771
Abstract: Long‐term or heavy use of glucocorticoids can cause severe necrosis of the femoral head, but the underlying mechanisms are still unclear. Recent studies have found that mitochondrial dynamics play an important role in femoral head… read more here.
Keywords: apoptosis; mitochondrial dynamics; dexamethasone; cell ... See more keywords
Role of Mitochondria‐Associated ER in Apoptosis
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.70105
Abstract: Apoptosis represents a critical noninflammatory mechanism for cell clearance in both physiological and pathological contexts, precisely regulated through the balance between proapoptotic and antiapoptotic signaling. Three well‐characterized apoptotic pathways have been identified: (1) the intrinsic… read more here.
Keywords: mitochondrial dynamics; role mitochondria; mitochondria associated; associated apoptosis ... See more keywords
Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24538
Abstract: Mitochondria are classically known to be the cellular energy producers, but a renewed appreciation for these organelles has developed with the accumulating discoveries of additional functions. The importance of mitochondria within the brain has been… read more here.
Keywords: dynamics regulation; regulation neurogenesis; mitochondrial dynamics; brain ... See more keywords
The mito::mKate2 mouse: A far‐red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo
Sign Up to like & getrecommendations! Published in 2018 at "genesis"
DOI: 10.1002/dvg.23087
Abstract: Mitochondria are incredibly dynamic organelles that undergo continuous fission and fusion events to control morphology, which profoundly impacts cell physiology including cell cycle progression. This is highlighted by the fact that most major human neurodegenerative… read more here.
Keywords: mitochondrial dynamics; reporter mouse; mouse; mito mkate2 ... See more keywords
Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia
Sign Up to like & getrecommendations! Published in 2017 at "Human Mutation"
DOI: 10.1002/humu.23262
Abstract: We report here the first families carrying recessive variants in the MSTO1 gene: compound heterozygous mutations were identified in two sisters and in an unrelated singleton case, who presented a multisystem complex phenotype mainly characterized… read more here.
Keywords: cause mitochondrial; recessive mutations; mutations msto1; msto1 cause ... See more keywords
Impairment of mitochondrial dynamics involved in iron oxide nanoparticle‐induced dysfunction of dendritic cells was alleviated by autophagy inhibitor 3‐methyladenine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3933
Abstract: Iron oxide nanoparticles are nanomaterials that are used extensively in the biomedical field, but they are associated with adverse effects, including mitochondrial toxicity. Mitochondrial homeostasis is achieved through dynamic stability based on two sets of… read more here.
Keywords: autophagy inhibitor; nanoparticle induced; iron oxide; dendritic cells ... See more keywords
Mitohormesis and mitochondrial dynamics in the regulation of stem cell fate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30820
Abstract: The ability of stem cells for self‐renewing, differentiation, and regeneration of injured tissues is believed to occur via the hormetic modulation of nuclear/mitochondrial signal transductions. The evidence now indicates that in damaged tissues, the mitochondria… read more here.
Keywords: cell fate; cell; stem cell; mitochondrial dynamics ... See more keywords
Research progress on ncRNAs regulation of mitochondrial dynamics in diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30878
Abstract: Diabetes mellitus and its complications are major health concerns worldwide that should be routinely monitored for evaluating disease progression. And there is currently much evidence to suggest a critical role for mitochondria in the common… read more here.
Keywords: mitochondrial dynamics; regulation mitochondrial; research progress;
Mitochondrial dynamics in pulmonary disease: Implications for the potential therapeutics
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31370
Abstract: Mitochondria are dynamic organelles that continuously undergo fusion/fission to maintain normal cell physiological activities and energy metabolism. When mitochondrial dynamics is unbalanced, mitochondrial homeostasis is broken, thus damaging mitochondrial function. Accumulating evidence demonstrates that impairment… read more here.
Keywords: disease; pulmonary diseases; mitochondrial dynamics; dynamics pulmonary ... See more keywords
Emerging mitochondrial‐mediated mechanisms involved in oligodendrocyte development
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25151
Abstract: Oligodendrocytes are the myelinating glia of the central nervous system and are generated after oligodendrocyte progenitor cells (OPCs) transition into pre‐oligodendrocytes and then into myelinating oligodendrocytes. Myelin is essential for proper signal transmission within the… read more here.
Keywords: development; oligodendrocyte development; mediated mechanisms; mitochondrial mediated ... See more keywords
USP4-Deubiquitinated PGAM5 Regulates Mitochondrial Dynamics in the Progression of Esophageal Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular carcinogenesis"
DOI: 10.1002/mc.70055
Abstract: This study explored the effect of ubiquitin‐specific protease 4 (USP4) on mitochondrial dynamics in esophageal squamous cell carcinoma (ESCC). USP4 and phosphoglycerate mutase 5 (PGAM5) expression in ESCC tissues was measured. ESCC cells were subjected… read more here.
Keywords: esophageal squamous; mitochondrial dynamics; usp4; cell ... See more keywords