Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway
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DOI: 10.1155/2019/9165214
Abstract: The mitochondria represent an integration and amplification hub for various death pathways including that mediated by granzyme B (GB), a granule enzyme expressed by cytotoxic lymphocytes. GB activates the proapoptotic B cell CLL/lymphoma 2 (Bcl-2)… read more here.
Keywords: mitochondrial entry; death; death pathway; cell death ... See more keywords