Developmental regression and mitochondrial function in children with autism
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51034
Abstract: Developmental regression (DR) occurs in about one‐third of children with Autism Spectrum Disorder (ASD) yet it is poorly understood. Current evidence suggests that mitochondrial function in not normal in many children with ASD. However, the… read more here.
Keywords: mitochondrial function; regression mitochondrial; children autism; function ... See more keywords
(p‐ClPhSe)2 Reduces Hepatotoxicity Induced by Monosodium Glutamate by Improving Mitochondrial Function in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25938
Abstract: It is has been demonstrated that mitochondrial dysfunction, oxidative stress, and chronic inflammatory process are associated with progress of morbid obesity in human patients. For this reason, the searching for safe and effective antiobesity drugs… read more here.
Keywords: induced monosodium; mitochondrial function; monosodium glutamate;
Curcumin induces concentration‐dependent alterations in mitochondrial function through ROS in C2C12 mouse myoblasts
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27370
Abstract: Curcumin exhibits antioxidant properties in normal cells where the uptake is low, unlike in tumor cells where uptake is high and curcumin increases reactive oxygen species (ROS) production and cell death. Mitochondria are the main… read more here.
Keywords: mitochondrial function; ros levels; concentration; cell ... See more keywords
Human placenta‐derived mesenchymal stem cells induce trophoblast invasion via dynamic effects on mitochondrial function
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30330
Abstract: The trophoblast is a critical cell for placental development and embryo implantation in the placenta. We previously reported that placenta‐derived mesenchymal stem cells (PD‐MSCs) increase trophoblast invasion through several signaling pathways. However, the paracrine effects… read more here.
Keywords: derived mesenchymal; trophoblast invasion; invasion; mitochondrial function ... See more keywords
Nampt affects mitochondrial function in aged oocytes by mediating the downstream effector FoxO3a.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30532
Abstract: Maternal aging can impair the quality and decrease the developmental competence of ovulated oocytes. In this study, compromised germinal vesicle breakdown (GVBD) was found in aged mice oocytes. Furthermore, we observed increased reactive oxygen species… read more here.
Keywords: mitochondrial function; foxo3a; affects mitochondrial; nampt affects ... See more keywords
Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12570
Abstract: Propionic acidemia (PA, OMIM 606054) is a devastating inborn error of metabolism arising from mutations that reduce the activity of the mitochondrial enzyme propionyl‐CoA carboxylase (PCC). The defects in PCC reduce the concentrations of nonesterified… read more here.
Keywords: mitochondrial function; bbp 671; coa; mouse model ... See more keywords
Time‐dependent loss of mitochondrial function precedes progressive histologic cartilage degeneration in a rabbit meniscal destabilization model
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23327
Abstract: The goals of this work were to characterize progression of osteoarthritic cartilage degeneration in a rabbit medial meniscus destabilization (MMD) model and then to use the model to identify pre‐histologic disruptions in chondrocyte metabolism under… read more here.
Keywords: mitochondrial function; pathology; model; degeneration ... See more keywords
Mitochondrial function of human embryo: Decline in their quality with maternal aging
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12491
Abstract: Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo. read more here.
Keywords: function; human embryo; embryo decline; function human ... See more keywords
Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2126
Abstract: Monolayer culture is integral to many cell‐based cartilage repair strategies, but chondrocytes lose regenerative potential with increasing duration in vitro. This coincides with elevated reactive oxygen species (ROS) levels and a bioenergetic transformation characterized by… read more here.
Keywords: oxygen; medicine; reactive oxygen; oxygen species ... See more keywords
Para-phenylenediamine deteriorates oocyte quality by impairing mitochondrial function.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23528
Abstract: Several studies demonstrate that para-phenylenediamine (PPD) is often added to permanent oxidative hair dyes. Sub-chronic topical exposure to PPD in male rats damages their testicular function; however, little is known about the effects of PPD… read more here.
Keywords: ppd; function; para phenylenediamine; mitochondrial function ... See more keywords
Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington's Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7825-0_19
Abstract: Mitochondrial dysfunction has gained a preponderant role in the pathogenesis of Huntington's disease (HD). Mutant huntingtin (mHTT) directly interacts with mitochondria in a deleterious manner. As the central hub of the cell, not only mitochondrial… read more here.
Keywords: assessing mitochondrial; mitochondrial function; huntington disease; function vitro ... See more keywords