The activator/repressor Hap1 binds to the yeast eIF5A‐encoding gene TIF51A to adapt its expression to the mitochondrial functional status
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DOI: 10.1002/1873-3468.14366
Abstract: Mitochondrial activity adapts to cellular energetic and metabolic demands; its dysfunction is a hallmark of ageing and many human diseases. The evolutionarily conserved translation elongation factor eIF5A is involved in maintaining mitochondrial function. In humans,… read more here.
Keywords: functional status; repressor; mitochondrial functional; expression ... See more keywords
Hyaluronan Induces a Mitochondrial Functional Switch in Fast-Proliferating Human Mesenchymal Stem Cells
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DOI: 10.15283/ijsc19004
Abstract: Background and Objectives Hyaluronan preserves the proliferation and differentiation potential of mesenchymal stem cells. Supplementation of low-concentration hyaluronan (SHA) in stem cells culture medium increases its proliferative rate, whereas coated-surface hyaluronan (CHA) maintains cells in… read more here.
Keywords: mitochondrial functional; mesenchymal stem; proliferating human; stem ... See more keywords