Differentially expressed mitochondrial genes in breast cancer cells: Potential new targets for anti-cancer therapies.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2016.10.005
Abstract: It has been reported that tumor growth and proliferation correspond to mitochondrial dysfunction and that the tumor cellular microenvironment plays a key role in tumor progression, representing an area that might be manipulated to confer… read more here.
Keywords: mitochondrial genes; stromal cells; breast cancer; cancer ... See more keywords
Primers targeting mitochondrial genes of avian haemosporidians: PCR detection and differential DNA amplification of parasites belonging to different genera.
Sign Up to like & getrecommendations! Published in 2018 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2018.02.003
Abstract: Haemosporida is a diverse group of vector-borne parasitic protozoa, ubiquitous in terrestrial vertebrates worldwide. The renewed interest in their diversity has been driven by the extensive use of molecular methods targeting mitochondrial genes. Unfortunately, most… read more here.
Keywords: detection; mitochondrial genes; dna; different genera ... See more keywords
Mitochondrial genes are altered in blood early in Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2016.12.029
Abstract: Although mitochondrial dysfunction is a consistent feature of Alzheimer's disease in the brain and blood, the molecular mechanisms behind these phenomena are unknown. Here we have replicated our previous findings demonstrating reduced expression of nuclear-encoded… read more here.
Keywords: mitochondrial genes; encoded oxphos; alzheimer disease; disease ... See more keywords
Differential RNA Editing of Mitochondrial Genes in WA-Cytoplasmic Based Male Sterile Line Pusa 6A, and Its Maintainer and Restorer Lines
Sign Up to like & getrecommendations! Published in 2019 at "Rice Science"
DOI: 10.1016/j.rsci.2019.08.002
Abstract: Abstract RNA editing changes the nucleotides at the transcript level of mitochondrial genes which results in synthesis of functional proteins. This study was designed to find the editing sites which could be implicated in male… read more here.
Keywords: mitochondrial genes; line; editing sites; maintainer ... See more keywords
Molecular genetic diversity and bioinformatic analysis of Leucocytozoon sabrazesi based on the mitochondrial genes cytb, coxI and coxIII and co-infection of Plasmodium spp.
Sign Up to like & getrecommendations! Published in 2022 at "Parasite"
DOI: 10.1051/parasite/2022022
Abstract: Leucocytozoon sabrazesi is an intracellular haemoprotozoan parasite responsible for leucocytozoonosis, which is transmitted by insect vectors and affects chickens in tropical and subtropical areas in many countries. It causes huge economic losses due to decreased… read more here.
Keywords: cytb coxi; plasmodium spp; coxi coxiii; analysis ... See more keywords
Character-based diagnostic keys, molecular identification and phylogenetic relationships of threadfin breams (family: Nemipteridae) based on mitochondrial genes from the Southern coromandel Coast, India.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2040522
Abstract: DNA barcoding, primarily focusing on cytochrome c oxidase subunit I (COI) gene has been appraised as an effective tool for species identification. In this study, we focused on the marine fishes of Family Nemipteridae, one… read more here.
Keywords: character based; identification; coromandel coast; family nemipteridae ... See more keywords
Coding palindromes in mitochondrial genes of Nematomorpha
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz517
Abstract: Abstract Inverted repeats are common DNA elements, but they rarely overlap with protein-coding sequences due to the ensuing conflict with the structure and function of the encoded protein. We discovered numerous perfect inverted repeats of… read more here.
Keywords: mitochondrial genes; palindromes mitochondrial; coding palindromes; inverted repeats ... See more keywords
Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16387
Abstract: Acute rejection after heart transplantation increases the risk of chronic dysfunction. Disturbances in mitochondrial function may play a contributory role, however, the relationship between histological signs of rejection in the human transplanted heart and expression… read more here.
Keywords: allograft rejection; mitochondrial genes; circulating mitochondrial; mcu ... See more keywords
Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/8401924
Abstract: Pulmonary arterial hypertension (PAH) is a severe and progressive disease that affects the heart and lungs and a global health concern that impacts individuals and society. Studies have reported that some proteins related to mitochondrial… read more here.
Keywords: pah; rat model; arterial hypertension; pulmonary arterial ... See more keywords
Positive Selection Drove the Adaptation of Mitochondrial Genes to the Demands of Flight and High-Altitude Environments in Grasshoppers
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00605
Abstract: The molecular evolution of mitochondrial genes responds to changes in energy requirements and to high altitude adaptation in animals, but this has not been fully explored in invertebrates. The evolution of atmospheric oxygen content from… read more here.
Keywords: mitochondrial genes; energy; positive selection; selection ... See more keywords
Non-coding regions of nuclear-DNA-encoded mitochondrial genes and intergenic sequences are targeted by autoantibodies in breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.970619
Abstract: Autoantibodies against mitochondrial-derived antigens play a key role in chronic tissue inflammation in autoimmune disorders and cancers. Here, we identify autoreactive nuclear genomic DNA (nDNA)-encoded mitochondrial gene products (GAPDH, PKM2, GSTP1, SPATA5, MFF, TSPOAP1, PHB2,… read more here.
Keywords: intergenic sequences; encoded mitochondrial; breast cancer; coding regions ... See more keywords