Articles with "mitochondrial genes" as a keyword



Differentially expressed mitochondrial genes in breast cancer cells: Potential new targets for anti-cancer therapies.

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Published in 2017 at "Gene"

DOI: 10.1016/j.gene.2016.10.005

Abstract: It has been reported that tumor growth and proliferation correspond to mitochondrial dysfunction and that the tumor cellular microenvironment plays a key role in tumor progression, representing an area that might be manipulated to confer… read more here.

Keywords: mitochondrial genes; stromal cells; breast cancer; cancer ... See more keywords

Primers targeting mitochondrial genes of avian haemosporidians: PCR detection and differential DNA amplification of parasites belonging to different genera.

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Published in 2018 at "International journal for parasitology"

DOI: 10.1016/j.ijpara.2018.02.003

Abstract: Haemosporida is a diverse group of vector-borne parasitic protozoa, ubiquitous in terrestrial vertebrates worldwide. The renewed interest in their diversity has been driven by the extensive use of molecular methods targeting mitochondrial genes. Unfortunately, most… read more here.

Keywords: detection; mitochondrial genes; dna; different genera ... See more keywords

Mitochondrial genes are altered in blood early in Alzheimer's disease

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Published in 2017 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2016.12.029

Abstract: Although mitochondrial dysfunction is a consistent feature of Alzheimer's disease in the brain and blood, the molecular mechanisms behind these phenomena are unknown. Here we have replicated our previous findings demonstrating reduced expression of nuclear-encoded… read more here.

Keywords: mitochondrial genes; encoded oxphos; alzheimer disease; disease ... See more keywords
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Differential RNA Editing of Mitochondrial Genes in WA-Cytoplasmic Based Male Sterile Line Pusa 6A, and Its Maintainer and Restorer Lines

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Published in 2019 at "Rice Science"

DOI: 10.1016/j.rsci.2019.08.002

Abstract: Abstract RNA editing changes the nucleotides at the transcript level of mitochondrial genes which results in synthesis of functional proteins. This study was designed to find the editing sites which could be implicated in male… read more here.

Keywords: mitochondrial genes; line; editing sites; maintainer ... See more keywords

Multiomics identification of ALDH9A1 as a crucial immunoregulatory molecule involved in calcific aortic valve disease

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-75115-8

Abstract: Mitochondrial dysfunction and immune cell infiltration play crucial yet incompletely understood roles in the pathogenesis of calcific aortic valve disease (CAVD). This study aimed to identify immune-related mitochondrial genes critical to the pathological process of… read more here.

Keywords: mitochondrial genes; valve disease; aortic valve; calcific aortic ... See more keywords

Mapping key mitochondrial genes in Alzheimer’s disease through human tissue and iPSC derived neurons

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-27019-4

Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative condition that has become a global health challenge due to an aging world population and no available effective treatment. Mitochondrial dysfunction plays a crucial role in the development… read more here.

Keywords: alzheimer disease; disease; derived neurons; mitochondrial genes ... See more keywords

Molecular genetic diversity and bioinformatic analysis of Leucocytozoon sabrazesi based on the mitochondrial genes cytb, coxI and coxIII and co-infection of Plasmodium spp.

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Published in 2022 at "Parasite"

DOI: 10.1051/parasite/2022022

Abstract: Leucocytozoon sabrazesi is an intracellular haemoprotozoan parasite responsible for leucocytozoonosis, which is transmitted by insect vectors and affects chickens in tropical and subtropical areas in many countries. It causes huge economic losses due to decreased… read more here.

Keywords: cytb coxi; plasmodium spp; coxi coxiii; analysis ... See more keywords

Character-based diagnostic keys, molecular identification and phylogenetic relationships of threadfin breams (family: Nemipteridae) based on mitochondrial genes from the Southern coromandel Coast, India.

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Published in 2022 at "Animal biotechnology"

DOI: 10.1080/10495398.2022.2040522

Abstract: DNA barcoding, primarily focusing on cytochrome c oxidase subunit I (COI) gene has been appraised as an effective tool for species identification. In this study, we focused on the marine fishes of Family Nemipteridae, one… read more here.

Keywords: character based; identification; coromandel coast; family nemipteridae ... See more keywords
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Coding palindromes in mitochondrial genes of Nematomorpha

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Published in 2019 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkz517

Abstract: Abstract Inverted repeats are common DNA elements, but they rarely overlap with protein-coding sequences due to the ensuing conflict with the structure and function of the encoded protein. We discovered numerous perfect inverted repeats of… read more here.

Keywords: mitochondrial genes; palindromes mitochondrial; coding palindromes; inverted repeats ... See more keywords

Circulating mitochondrial genes detect acute cardiac allograft rejection: Role of the mitochondrial calcium uniporter complex

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Published in 2020 at "American Journal of Transplantation"

DOI: 10.1111/ajt.16387

Abstract: Acute rejection after heart transplantation increases the risk of chronic dysfunction. Disturbances in mitochondrial function may play a contributory role, however, the relationship between histological signs of rejection in the human transplanted heart and expression… read more here.

Keywords: allograft rejection; mitochondrial genes; circulating mitochondrial; mcu ... See more keywords

Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/8401924

Abstract: Pulmonary arterial hypertension (PAH) is a severe and progressive disease that affects the heart and lungs and a global health concern that impacts individuals and society. Studies have reported that some proteins related to mitochondrial… read more here.

Keywords: pah; rat model; arterial hypertension; pulmonary arterial ... See more keywords