The Structural Asymmetry of Mitochondrial Hsp90 (Trap1) Determines Fine Tuning of Functional Dynamics.
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DOI: 10.1021/acs.jctc.7b00766
Abstract: The Hsp90 family of molecular chaperones oversees the folding of a wide range of client proteins. Hsp90 is a homodimer, whose conformational states and functions are regulated by ATP-binding and hydrolysis. The crystal structure of… read more here.
Keywords: asymmetry; hydrolysis; structural asymmetry; trap1 ... See more keywords