Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-05-0284
Abstract: The apical surface of the terminally differentiated mammalian urothelial umbrella cell is mechanically stable and highly impermeable, in part due to its coverage by urothelial plaques consisting of 2D crystals of uroplakin particles. The mechanism… read more here.
Keywords: formation; lipid droplet; mitochondrial lipid; mechanism ... See more keywords
Short-Term High-Fat Feeding Does Not Alter Mitochondrial Lipid Respiratory Capacity but Triggers Mitophagy Response in Skeletal Muscle of Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.651211
Abstract: Lipid overload of the mitochondria is linked to the development of insulin resistance in skeletal muscle which may be a contributing factor to the progression of type 2 diabetes during obesity. The targeted degradation of… read more here.
Keywords: fat diet; skeletal muscle; high fat; mitochondrial lipid ... See more keywords
Mitochondrial Lipid Signaling and Adaptive Thermogenesis
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DOI: 10.3390/metabo11020124
Abstract: Thermogenesis is an energy demanding process by which endotherms produce heat to maintain their body temperature in response to cold exposure. Mitochondria in the brown and beige adipocytes play a key role in thermogenesis, as… read more here.
Keywords: thermogenesis; signaling adaptive; lipid signaling; mitochondrial lipid ... See more keywords