Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cell International"
DOI: 10.1186/s12935-019-1037-1
Abstract: BackgroundCisplatin plus pemetrexed combination therapy is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer (NSCLC). However, advanced NSCLC has a 5-year survival rate of below 10%, which is mainly due to… read more here.
Keywords: mitochondrial mass; treatment; cisplatin; mito ... See more keywords
Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes
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DOI: 10.1249/jes.0000000000000307
Abstract: Ketogenic diets improve muscle mitochondrial mass and function with age or disease, but not in athletes with high mitochondrial quality. As humans age, we lose skeletal muscle mass, even in the absence of disease (sarcopenia),… read more here.
Keywords: function; diets mitochondrial; ketogenic diets; mitochondrial function ... See more keywords
A 1-Month Ketogenic Diet Increased Mitochondrial Mass in Red Gastrocnemius Muscle, but Not in the Brain or Liver of Middle-Aged Mice
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DOI: 10.3390/nu13082533
Abstract: Alterations in markers of mitochondrial content with ketogenic diets (KD) have been reported in tissues of rodents, but morphological quantification of mitochondrial mass using transmission electron microscopy (TEM), the gold standard for mitochondrial quantification, is… read more here.
Keywords: gastrocnemius muscle; red gastrocnemius; mitochondrial mass; mass ... See more keywords