Mitochondrial Dysfunction in Mitochondrial Medicine: Current Limitations, Pitfalls, and Tomorrow.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1266-8_1
Abstract: Until recently restricted to hereditary mitochondrial diseases, mitochondrial dysfunction is now recognized as a key player and strategic factor in the pathophysiological of many human diseases, ranging from the metabolism, vascular, cardiac, and neurodegenerative diseases… read more here.
Keywords: medicine; medicine current; mitochondrial medicine; dysfunction ... See more keywords
Radboud Centre for Mitochondrial Medicine Pediatric MRI score.
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DOI: 10.1016/j.mito.2016.11.008
Abstract: We developed the first user-friendly, semi-quantitative, and quick-to-perform Radboud Centre for Mitochondrial Medicine Pediatric MRI score (RCMM-PMRIS), focusing on the six most commonly described neuroimaging abnormalities in the literature. The RCMM-PMRIS was validated through individual… read more here.
Keywords: medicine; radboud centre; mitochondrial medicine; centre mitochondrial ... See more keywords
Advances in Mitochondrial Medicine and Translational Research.
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DOI: 10.1016/j.mito.2021.08.001
Abstract: Current knowledge of mitochondrial biology and function has provided with tools and technologies that helped a better understanding of the molecular etiology of complex mitochondrial disorders. Dual genetic control of this subcellular organelle function regulates… read more here.
Keywords: medicine; research; mitochondrial medicine; mitochondrial biology ... See more keywords
Costs for mitochondrial medicine will remain high as long as mitochondrial disorders are misdiagnosed☆☆☆★★★
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2017.08.002
Abstract: We read with interest the article by McCormack et al. about frequency and costs of hospitalisations of mitochondrial disorder (MID) patients in California [1]. There are several reasons why the figures provided are underestimations. First,… read more here.
Keywords: medicine; costs mitochondrial; mitochondrial medicine; high long ... See more keywords
Mitochondrial Medicine: A Promising Therapeutic Option Against Various Neurodegenerative Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220830112408
Abstract: Abnormal mitochondrial morphology and metabolic dysfunction have been observed in many neurodegenerative disorders (NDDs). Mitochondrial dysfunction can be caused by aberrant mitochondrial DNA, mutant nuclear proteins that interact with mitochondria directly or indirectly, or unknown… read more here.
Keywords: promising therapeutic; mitochondrial medicine; therapeutic option; medicine ... See more keywords