Tumor Microenvironment and Metabolism: Role of the Mitochondrial Melatonergic Pathway in Determining Intercellular Interactions in a New Dynamic Homeostasis
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DOI: 10.3390/ijms24010311
Abstract: There is a growing interest in the role of alterations in mitochondrial metabolism in the pathoetiology and pathophysiology of cancers, including within the array of diverse cells that can form a given tumor microenvironment. The… read more here.
Keywords: intercellular interactions; role; tumor microenvironment; mitochondrial melatonergic ... See more keywords
Depression Pathophysiology: Astrocyte Mitochondrial Melatonergic Pathway as Crucial Hub
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DOI: 10.3390/ijms24010350
Abstract: Major depressive disorder (MDD) is widely accepted as having a heterogenous pathophysiology involving a complex mixture of systemic and CNS processes. A developmental etiology coupled to genetic and epigenetic risk factors as well as lifestyle… read more here.
Keywords: melatonergic pathway; depression pathophysiology; mitochondrial melatonergic; astrocyte mitochondrial ... See more keywords