[6]‐Gingerol–induced cell cycle arrest, reactive oxygen species generation, and disruption of mitochondrial membrane potential are associated with apoptosis in human gastric cancer (AGS) cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22206
Abstract: Ginger (Zingiber officinale Roscoe), a monocotyledonous herb, is widely used as an herbal medicine owing to the phytoconstituents it possesses. In the current study, the quantity of [6]‐gingerol, the major phenolic ketone, in the fresh… read more here.
Keywords: reactive oxygen; oxygen species; gingerol; human gastric ... See more keywords
Analysis of Mitochondrial Membrane Fusion GTPase OPA1 Expressed by the Silkworm Expression System.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0676-6_9
Abstract: Mitochondria are highly dynamic organelles, which move and fuse to regulate their shape, size, and fundamental function. The dynamin-related GTPases play a critical role in mitochondrial membrane fusion. In vitro reconstitution of membrane fusion using… read more here.
Keywords: opa1; membrane fusion; expression; fusion ... See more keywords
Assessment of Mitochondrial Membrane Potential and NADH Redox State in Acute Brain Slices.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1266-8_14
Abstract: Brain is one of the most energy-demanding organs. Energy in the form of ATP is produced in brain cells predominantly in oxidative phosphorylation coupled to mitochondrial respiration. Any alteration of the mitochondrial metabolism or prolonged… read more here.
Keywords: acute brain; nadh; assessment mitochondrial; membrane potential ... See more keywords
Comparative characterization of rat hippocampal plasma membrane and mitochondrial membrane proteomes based on a sequential digestion-centered combinative strategy
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-0995-9
Abstract: AbstractPlasma membrane (PM) and mitochondrial membrane (MM) proteins of rat hippocampal neurons were identified and comparatively characterized on the basis of a sequential digestion-centered combinative strategy for sample treatment. A total of 478 membrane proteins… read more here.
Keywords: membrane mitochondrial; digestion centered; rat hippocampal; mitochondrial membrane ... See more keywords
Factors affecting staining to discriminate between bull sperm with greater and lesser mitochondrial membrane potential.
Sign Up to like & getrecommendations! Published in 2018 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.12.007
Abstract: The sperm mitochondrial membrane potential (MMP) is usually evaluated using the JC-1 dye. This study aimed to verify the effect of incubation temperature (25 °C or 38 °C), incubation time (10, 30, and 45 min), JC-1 stain concentration… read more here.
Keywords: hmmp; incubation; min; membrane potential ... See more keywords
Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.135
Abstract: Molecular hydrogen (H2) is recognized as a medical gas applicable to numerous diseases including neurodegenerative diseases, metabolic disorders, and rheumatoid arthritis. Although the efficacy of H2 is reportedly attributed to its scavenging capability against the… read more here.
Keywords: electron; membrane potential; mitochondrial membrane; superoxide generation ... See more keywords
New imidazoles cause cellular toxicity by impairing redox balance, mitochondrial membrane potential, and modulation of HIF-1α expression.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.059
Abstract: BACKGROUND Our previous reports demonstrated the prospects of a new series of imidazoles as a source of alternative anti-parasite treatments, thus warranting further studies that include toxicity profiling. OBJECTIVE In this study, we evaluated three… read more here.
Keywords: cellular toxicity; toxicity; compound; membrane potential ... See more keywords
Allosteric Regulation of NCLX by Mitochondrial Membrane Potential Links the Metabolic State and Ca2+ Signaling in Mitochondria.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.084
Abstract: Calcium is a key regulator of mitochondrial function under both normal and pathological conditions. The mechanisms linking metabolic activity to mitochondrial Ca2+ signaling remain elusive, however. Here, by monitoring mitochondrial Ca2+ transients while manipulating mitochondrial… read more here.
Keywords: ca2 signaling; ca2; membrane potential; mitochondrial membrane ... See more keywords
Independent roles of CGRP in cardioprotection and hemodynamic regulation in ischemic postconditioning
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.03.031
Abstract: ABSTRACT Calcitonin gene‐related peptide (CGRP) may participate in ischemic post‐conditioning (IPost) attenuating myocardial ischemia/reperfusion injury. However, the molecular mechanism underlying the effect of CGRP is still elusive. In this study, we evaluated the difference in… read more here.
Keywords: reactive oxygen; oxygen species; cgrp; cytosolic reactive ... See more keywords
SU27 MOOD STABILIZERS IMPROVE CELL VIABILITY AND MITOCHONDRIAL MEMBRANE POTENTIAL IN VITRO
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.216
Abstract: Background Lithium and valproate are the first line of drugs to treat Bipolar Affective Disorder (BPAD). The role of mitochondria in BPAD pathophysiology has often been investigated. The current study aims to explore the effects… read more here.
Keywords: bpad; mood; membrane potential; mitochondrial membrane ... See more keywords
Effect of mitochondrial apoptotic activation through the mitochondrial membrane permeability transition pore on yak meat tenderness during postmortem aging.
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DOI: 10.1016/j.foodchem.2017.04.185
Abstract: The effect of membrane permeability transition pore dependent mitochondrial apoptotic activation on yak meat tenderness was investigated. Results indicate that MPTP opening increased significantly and the mitochondrial membrane potential decreased markedly in the early aging… read more here.
Keywords: yak meat; mitochondrial membrane; mitochondrial apoptotic; meat tenderness ... See more keywords