OGT-related mitochondrial motility is associated with sex differences and exercise effects in depression induced by prenatal exposure to glucocorticoids.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2017.09.053
Abstract: BACKGROUND Prenatal exposure to glucocorticoids (GCs) has been found to trigger abnormal behaviors and deleterious neurological effects on offspring both in animals and in humans. The sex differences in depression have been replicated in numerous… read more here.
Keywords: mitochondrial motility; depression; sex differences; exposure ... See more keywords
Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.852245
Abstract: Microtubule-based transport provides mitochondria to distant regions of neurons and is essential for neuronal health. To identify compounds that increase mitochondrial motility, we screened 1,641 small-molecules in a high-throughput screening platform. Indirubin and cantharidin increased… read more here.
Keywords: axonal mitochondria; transport axonal; protein phosphatase; mitochondrial motility ... See more keywords