Live imaging reveals the dynamics and regulation of mitochondrial nucleoids during the cell cycle in Fucci2-HeLa cells
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DOI: 10.1038/s41598-017-10843-8
Abstract: Mitochondrial DNA (mtDNA) is organized in nucleoprotein complexes called mitochondrial nucleoids (mt-nucleoids), which are critical units of mtDNA replication and transmission. In humans, several hundreds of mt-nucleoids exist in a cell. However, how numerous mt-nucleoids… read more here.
Keywords: cycle; mtdna replication; mitochondrial nucleoids; cell cycle ... See more keywords
SYBR Gold dye enables preferential labelling of mitochondrial nucleoids and their time-lapse imaging by structured illumination microscopy
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DOI: 10.1371/journal.pone.0203956
Abstract: Mitochondrial DNA molecules coated with proteins form compact particles called mitochondrial nucleoids. They are redistributed within mitochondrial network undergoing morphological changes. The straightforward technique to characterize nucleoids’ motions is fluorescence microscopy. Mitochondrial nucleoids are commonly… read more here.
Keywords: lapse imaging; labelling mitochondrial; sybr gold; microscopy ... See more keywords