Mitochondrial outer membrane permeabilization at the single molecule level
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-021-03771-4
Abstract: Apoptotic cell death is essential for development, immune function or tissue homeostasis, and its mis-regulation is linked to various diseases. Mitochondrial outer membrane permeabilization (MOMP) is a central event in the intrinsic apoptotic pathway and… read more here.
Keywords: molecule; single molecule; outer membrane; membrane permeabilization ... See more keywords
Miro, a mitochondrial outer membrane protein interacts with Alzheimer’s disease related genes in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.350
Abstract: During development, cortical interneurons generated from the ventral telencephalon migrate tangentially into the dorsal telencephalon. AlthoughAchaete-scute family bHLH transcription factor 1 (Ascl1) plays important roles in the developing telencephalon, whether Ascl1 regulates tangential migration remains… read more here.
Keywords: tangential migration; outer membrane; ascl1; dorsal telencephalon ... See more keywords
SPOTting stress at the mitochondrial outer membrane.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular cell"
DOI: 10.1016/j.molcel.2022.02.030
Abstract: Li et al. (2022) discover that Toxoplasma infection triggers remodeling of the mitochondrial outer membrane through generation of a mitochondrial subdomain termed "structure positive for outer mitochondrial membrane" (SPOT). read more here.
Keywords: mitochondrial outer; stress mitochondrial; membrane; outer ... See more keywords
Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-01-0044
Abstract: The anti-apoptotic Bcl-2 family protein Bcl-xL plays a critical role in cell survival by protecting the integrity of the mitochondrial outer membrane (MOM). The mechanism through which Bcl-xL is recruited to the MOM has not… read more here.
Keywords: mitochondrial outer; outer membrane; retromer; membrane ... See more keywords
A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection
Sign Up to like & getrecommendations! Published in 2017 at "Infection and Immunity"
DOI: 10.1128/iai.01046-16
Abstract: ABSTRACT Coxiella burnetii, the causative agent of Q fever, establishes a unique lysosome-derived intracellular niche termed the Coxiella-containing vacuole (CCV). The Dot/Icm-type IVB secretion system is essential for the biogenesis of the CCV and the… read more here.
Keywords: coxiella; effector; outer membrane; mitochondrial outer ... See more keywords
The role of the mitochondrial outer membrane protein SLC25A46 in mitochondrial fission and fusion
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202301914
Abstract: The mitochondrial outer membrane protein SLC25A46 localizes to mitochondrial fusion and fission sites, and loss of function alters mitochondrial morphology and oligomerization states of MFN2 and OPA1. Mutations in SLC25A46 underlie a wide spectrum of… read more here.
Keywords: fission; fusion; mitochondrial outer; outer membrane ... See more keywords