LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "mitochondrial permeability" as a keyword



Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Sign Up to like & get
recommendations! Published in 2019 at "Brain and Behavior"

DOI: 10.1002/brb3.1501

Abstract: Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis. Mitochondrial permeability transition pore (mPTP) plays an important role in apoptosis, but it is unknown… read more here.

Keywords: sevoflurane postconditioning; hemorrhagic shock; mitochondrial permeability; transition pore ... See more keywords
Photo from wikipedia

Pharmacology of mitochondrial permeability transition pore inhibitors

Sign Up to like & get
recommendations! Published in 2019 at "Drug Development Research"

DOI: 10.1002/ddr.21593

Abstract: It is now firmly established that an important event in the formation of reperfusion injury of the heart is the opening of mitochondrial permeability transition pores (mPTPs), which changes the permeability of the mitochondria. mPTP… read more here.

Keywords: mptp; permeability; pharmacology; mitochondrial permeability ... See more keywords
Photo by qnerd from unsplash

Mitochondrial permeability transition in cardiac ischemia–reperfusion: whether cyclophilin D is a viable target for cardioprotection?

Sign Up to like & get
recommendations! Published in 2017 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-017-2502-4

Abstract: Growing number of studies provide strong evidence that the mitochondrial permeability transition pore (PTP), a non-selective channel in the inner mitochondrial membrane, is involved in the pathogenesis of cardiac ischemia–reperfusion and can be targeted to… read more here.

Keywords: cyclophilin; mitochondrial permeability; target; reperfusion ... See more keywords
Photo from wikipedia

Alleviation by GABAB Receptors of Neurotoxicity Mediated by Mitochondrial Permeability Transition Pore in Cultured Murine Cortical Neurons Exposed to N-Methyl-d-aspartate

Sign Up to like & get
recommendations! Published in 2017 at "Neurochemical Research"

DOI: 10.1007/s11064-017-2311-z

Abstract: Mitochondrial permeability transition pore (PTP) is supposed to at least in part participate in molecular mechanisms underlying the neurotoxicity seen after overactivation of N-methyl-d-aspartate (NMDA) receptor (NMDAR) in neurons. In this study, we have evaluated… read more here.

Keywords: methyl aspartate; nmda; neurotoxicity; mitochondrial permeability ... See more keywords
Photo by markusspiske from unsplash

Ultrafine Particulate Matter Increases Cardiac Ischemia/Reperfusion Injury via Mitochondrial Permeability Transition Pore

Sign Up to like & get
recommendations! Published in 2017 at "Cardiovascular Toxicology"

DOI: 10.1007/s12012-017-9402-6

Abstract: Ultrafine particulate matter (UFP) has been associated with increased cardiovascular morbidity and mortality. However, the mechanisms that drive PM-associated cardiovascular disease and dysfunction remain unclear. We examined the impact of oropharyngeal aspiration of 100 μg UFP… read more here.

Keywords: mitochondrial permeability; injury; ultrafine particulate; permeability transition ... See more keywords
Photo from wikipedia

Phenylglyoxal inhibition of the mitochondrial F1FO-ATPase activated by Mg2+ or by Ca2+ provides clues on the mitochondrial permeability transition pore.

Sign Up to like & get
recommendations! Published in 2020 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2020.108258

Abstract: Phenylglyoxal (PGO), known to cause post-translational modifications of Arg residues, was used to highlight the role of arginine residues of the F1FO-ATPase, which may be crucial to yield the mitochondrial permeability transition pore (mPTP). In… read more here.

Keywords: f1fo atpase; atpase; ca2; mitochondrial permeability ... See more keywords
Photo from wikipedia

Dysregulation of Mitochondrial Permeability Transition Pore (MPTP) is Associated with Enhanced ROS Production in Skeletal Muscle of an ALS Mouse Model

Sign Up to like & get
recommendations! Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.1759

Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease. Oxidative stress is implicated in ALS pathophysiology. Using ROS Brite™ 570, a cytosolic ROS detector, we found a significant increase in ROS production of muscle fibers… read more here.

Keywords: mptp; mitochondrial permeability; muscle; ros production ... See more keywords
Photo by curology from unsplash

Cyclophilin D regulation of the mitochondrial permeability transition pore.

Sign Up to like & get
recommendations! Published in 2022 at "Current opinion in physiology"

DOI: 10.1016/j.cophys.2022.100486

Abstract: The opening of the mitochondrial permeability transition pore (PTP) has been proposed to play a critical role in activating cell death in many settings, including cardiac ischemia and reperfusion. Although the identity of pore forming… read more here.

Keywords: ptp; transition pore; mitochondrial permeability; permeability transition ... See more keywords
Photo by raymondo600 from unsplash

Indium (III) induces isolated mitochondrial permeability transition by inhibiting proton influx and triggering oxidative stress.

Sign Up to like & get
recommendations! Published in 2017 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2017.08.012

Abstract: While Indium's toxicity to organs is realized, its effects on mitochondria are still under investigation. Mitochondrial permeability transition (MPT) is widely accepted in mitochondrial dysfunction approaches and its importance in metal-induced mitochondrial degradation has been… read more here.

Keywords: permeability; inhibiting proton; mitochondrial permeability; membrane ... See more keywords
Photo by curology from unsplash

Sirtuin 3 and mitochondrial permeability transition pore (mPTP): a systematic review.

Sign Up to like & get
recommendations! Published in 2022 at "Mitochondrion"

DOI: 10.1016/j.mito.2022.03.004

Abstract: Mitochondrial permeability transition pore (mPTP) is a channel that opens at the inner mitochondrial membrane under conditions of stress. Sirtuin 3 (Sirt3) is a mitochondrial deacetylase known to play a major role in stress resistance… read more here.

Keywords: review; transition pore; sirt3; mitochondrial permeability ... See more keywords
Photo from wikipedia

Mitochondrial permeability transition pore in sea urchin female gametes

Sign Up to like & get
recommendations! Published in 2018 at "Mechanisms of development"

DOI: 10.1016/j.mod.2018.07.008

Abstract: Mitochondrial permeability transition pore (MPTP) has been associated to calcium homeostasis and reactive oxygen species (ROS) generation in several cell types. While extensively investigated in somatic cells, there are few data regarding MPTP phenomenon in… read more here.

Keywords: urchin female; sea; sea urchin; mitochondrial permeability ... See more keywords