A method for assessing mitochondrial physiology using mechanically permeabilized flight muscle of Aedes aegypti mosquitoes.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.04.005
Abstract: Aedes aegypti is the most important and widespread vector of arboviruses, including dengue and zika. Insect dispersal through the flight activity is a key parameter that determines vector competence, and is energetically driven by oxidative… read more here.
Keywords: aedes aegypti; flight muscle; mitochondrial physiology; physiology ... See more keywords
Cancer/Testis Antigens into mitochondria: a hub between spermatogenesis, tumorigenesis and mitochondrial physiology adaptation.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.11.002
Abstract: Cancer/Testis Antigens (CTAs) genes are expressed only during spermatogenesis and tumorigenesis. Both processes share common specific metabolic adaptation related to energy supply, with a glucose to lactate gradient, leading to changes in mitochondrial physiology paralleling… read more here.
Keywords: spermatogenesis tumorigenesis; testis antigens; mitochondrial physiology; physiology ... See more keywords
An evolving roadmap: using mitochondrial physiology to help guide conservation efforts
Sign Up to like & getrecommendations! Published in 2024 at "Conservation Physiology"
DOI: 10.1093/conphys/coae063
Abstract: Mitochondrial processes play crucial roles in species’ responses to environmental variation. Here, we synthesize the methods and approaches involved in mitochondrial bioenergetics as tools to guide the field of conservation physiology. read more here.
Keywords: roadmap using; mitochondrial physiology; physiology; conservation ... See more keywords
Mitochondrial Physiology of Cellular Redox Regulations.
Sign Up to like & getrecommendations! Published in 2024 at "Physiological research"
DOI: 10.33549/physiolres.935269
Abstract: Mitochondria (mt) represent the vital hub of the molecular physiology of the cell, being decision-makers in cell life/death and information signaling, including major redox regulations and redox signaling. Now we review recent advances in understanding… read more here.
Keywords: redox regulations; mitochondrial physiology; redox; physiology ... See more keywords
Zagociguat prevented stressor-induced neuromuscular dysfunction, improved mitochondrial physiology, and increased exercise capacity in diverse mitochondrial respiratory chain disease zebrafish models
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1588426
Abstract: Background Zagociguat (zag) is a CNS-penetrant, soluble guanylate cyclase (sGC) stimulator that has been evaluated in phase 2a, with phase 2b ongoing, clinical studies of primary mitochondrial disease (PMD) subjects with mitochondrial encephalomyopathy, lactic acidosis,… read more here.
Keywords: mitochondrial physiology; disease; physiology; zag ... See more keywords
The impact of diet upon mitochondrial physiology (Review)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5191
Abstract: Mitochondria are considered the 'powerhouses' of cells, generating the essential energy in the form of adenosine triphosphate that they need for their energy demands. Nevertheless, their function is easily adaptable as regards the energy demands… read more here.
Keywords: impact diet; review; energy; mitochondrial physiology ... See more keywords