Current Challenges of Mitochondrial Potassium Channel Research
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.907015
Abstract: In this paper, the current challenges of mitochondrial potassium channels research were critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria has been substantial, some basic issues of this process remain unresolved.… read more here.
Keywords: potassium channels; potassium; mitochondrial potassium; potassium channel ... See more keywords
Mitochondrial Potassium Channels as Druggable Targets
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DOI: 10.3390/biom10081200
Abstract: Mitochondrial potassium channels have been described as important factors in cell pro-life and death phenomena. The activation of mitochondrial potassium channels, such as ATP-regulated or calcium-activated large conductance potassium channels, may have cytoprotective effects in… read more here.
Keywords: mitochondrial potassium; potassium channels; potassium; druggable targets ... See more keywords
Methods of Measuring Mitochondrial Potassium Channels: A Critical Assessment
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DOI: 10.3390/ijms23031210
Abstract: In this paper, the techniques used to study the function of mitochondrial potassium channels are critically reviewed. The majority of these techniques have been known for many years as a result of research on plasma… read more here.
Keywords: potassium channels; potassium; channels critical; mitochondrial potassium ... See more keywords
Alternative Targets for Modulators of Mitochondrial Potassium Channels
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DOI: 10.3390/molecules27010299
Abstract: Mitochondrial potassium channels control potassium influx into the mitochondrial matrix and thus regulate mitochondrial membrane potential, volume, respiration, and synthesis of reactive oxygen species (ROS). It has been found that pharmacological activation of mitochondrial potassium… read more here.
Keywords: potassium channels; potassium; channels alternative; alternative targets ... See more keywords