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Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_117
Abstract: Mitochondria are a major source of intracellular energy and reactive oxygen species in cells, but are also increasingly being recognized as a controller of cell death. Here, we review evidence of signal transduction control by…
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Keywords:
reactive oxygen;
oxygen species;
mitochondrial superoxide;
mitochondrial reactive ... See more keywords
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Published in 2021 at "Acta Pharmaceutica Sinica B"
DOI: 10.1016/j.apsb.2021.08.007
Abstract: Abstract Sulfonylureas are widely used oral anti-diabetic drugs. However, its long-term usage effects on patients’ lifespan remain controversial, with no reports of influence on animal longevity. Hence, the anti-aging effects of chlorpropamide along with glimepiride,…
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Keywords:
reactive oxygen;
aging effects;
mitochondrial reactive;
mitochondrial complex ... See more keywords
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Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2017.05.015
Abstract: While increased mitochondrial reactive oxygen species have been commonly implicated in a variety of disease states, their in vivo role in the pathogenesis of diabetic nephropathy remains controversial. Using a two-photon imaging approach with a genetically…
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Keywords:
reactive oxygen;
oxygen species;
redox;
mitochondrial reactive ... See more keywords
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Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2018.07.018
Abstract: Our aim was to elucidate the relationship between the rate of mitochondrial reactive oxygen species (mROS) formation and the reduction level of the mitochondrial coenzyme Q (mQ) pool under various levels of engagement of the…
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Keywords:
reduction;
reactive oxygen;
reduction level;
mitochondrial reactive ... See more keywords
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Published in 2018 at "Experimental Physiology"
DOI: 10.1113/ep087083
Abstract: What is the central question of this study? Do peripheral sensory neurons metabolize fat‐based fuel sources, and does a ketogenic diet modify these processes? What is the main finding and its importance We show that…
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Keywords:
reactive oxygen;
reduced mitochondrial;
fed ketogenic;
mitochondrial reactive ... See more keywords
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Published in 2022 at "Journal of immunology"
DOI: 10.4049/jimmunol.2101166
Abstract: γδ T cells reside at mucosal and epithelial barriers, and they often accumulate at sites of inflammation, both infectious and autoimmune, as well as in certain tumors. However, progress in understanding their function is considerably…
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Keywords:
synovial cell;
mitochondrial reactive;
ligand expression;
expression ... See more keywords