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   Articles with "mitochondrial respiratory" as a keyword



Reprogramming of Mitochondrial Respiratory Chain Complex by Targeting SIRT3‐COX4I2 Axis Attenuates Osteoarthritis Progression

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recommendations! Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202206144

Abstract: Mitochondrial homeostasis is of great importance for cartilage integrity and associated with the progression of osteoarthritis (OA); however, the underlying mechanisms are unknown. This study aims to investigate the role of mitochondrial deacetylation reaction and… read more here.

Keywords: respiratory chain; sirt3; progression; mitochondrial respiratory ... See more keywords

Docosahexaenoic acid increased MeCP2 mediated mitochondrial respiratory complexes II and III enzyme activities in cortical astrocytes

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recommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23002

Abstract: Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl‐CpG‐binding protein 2 (MeCP2) in the neurons and glial cells of the central nervous system. Currently, therapeutics for RTT is aimed at restoring… read more here.

Keywords: iii enzyme; docosahexaenoic acid; expression; dha ... See more keywords

Local Regulation of Mitochondrial Respiratory for Enhancing Photodynamic Therapy and Breaking Chemoresistance in Hypoxia.

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recommendations! Published in 2024 at "Small"

DOI: 10.1002/smll.202402956

Abstract: The hypoxic condition in solid tumors induces therapy resistance, limited therapeutic efficacy, and tumor recurrence, especially for chemotherapy and aerobic photodynamic therapy (PDT). To address this matter, an O2 regulator (SNP@Ato) is designed for breaking… read more here.

Keywords: breaking chemoresistance; mitochondrial respiratory; snp ato; hypoxia ... See more keywords

Alternative mitochondrial respiratory chains from two crustaceans: Artemia franciscana nauplii and the white shrimp, Litopenaeus vannamei

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recommendations! Published in 2018 at "Journal of Bioenergetics and Biomembranes"

DOI: 10.1007/s10863-018-9753-0

Abstract: Mitochondrial ATP is synthesized by coupling between the electron transport chain and complex V. In contrast, physiological uncoupling of these processes allows mitochondria to consume oxygen at high rates without ATP synthesis. Such uncoupling mechanisms… read more here.

Keywords: mitochondrial respiratory; franciscana nauplii; alternative redox; redox enzymes ... See more keywords

The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes

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recommendations! Published in 2024 at "Journal of Bioenergetics and Biomembranes"

DOI: 10.1007/s10863-023-09999-y

Abstract: During their long evolutionary history, jellyfish have faced changes in multiple environmental factors, to which they may selectively fix adaptations, allowing some species to survive and inhabit diverse environments. Previous findings have confirmed the jellyfish’s… read more here.

Keywords: mitochondrial respiratory; respiratory chain; respiratory; response environmental ... See more keywords

The oral administration of D-galactose induces abnormalities within the mitochondrial respiratory chain in the brain of rats

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recommendations! Published in 2017 at "Metabolic Brain Disease"

DOI: 10.1007/s11011-017-9972-9

Abstract: D-Galactose (D-gal) chronic administration via intraperitoneal and subcutaneous routes has been used as a model of aging and Alzheimer disease in rodents. Intraperitoneal and subcutaneous administration of D-gal causes memory impairments, a reduction in the… read more here.

Keywords: mitochondrial respiratory; administration; respiratory chain; respiratory ... See more keywords

Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies.

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recommendations! Published in 2018 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2018.06.029

Abstract: Skeletal muscle is a heterogeneous tissue and it is essential to know the methodological variation and reliability when measuring aspects of muscle function. We assessed the methodological and biological variation when measuring mitochondrial respiratory capacity… read more here.

Keywords: mitochondrial respiratory; biopsy; variation; muscle biopsies ... See more keywords

Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.

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recommendations! Published in 2019 at "Chemosphere"

DOI: 10.1016/j.chemosphere.2019.125099

Abstract: Our previous study showed that excessive fluoride (F) intake can induce liver dysfunction. The aim of this study was to investigate the mechanisms of F-induced mitochondrial damage resulting in liver dysfunction. Damaged mitochondrial ultrastructure and… read more here.

Keywords: mitochondrial respiratory; respiratory chain; dysfunction; liver dysfunction ... See more keywords

Quantitative proteomics reveals mitochondrial respiratory chain as a dominant target for carbon ion radiation: Delayed reactive oxygen species generation caused DNA damage

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recommendations! Published in 2019 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2018.10.449

Abstract: ABSTRACT Heavy ion radiotherapy has shown great promise for cancer therapy. Understanding the cellular response mechanism to heavy ion radiation is required to explore measures of overcoming devastating side effects. Here, we performed a quantitative… read more here.

Keywords: mitochondrial respiratory; ion radiation; respiratory chain; ion ... See more keywords

Thinned young apple polysaccharide improves hepatic metabolic disorder in high-fat diet-induced obese mice by activating mitochondrial respiratory functions

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recommendations! Published in 2017 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2017.03.055

Abstract: Abstract Apple polysaccharides have been previously demonstrated to have beneficial effects on hepatic metabolic functions. Approximately 1.9 million tons of young apples are thinned and abandoned annually in China, and whether the polysaccharide derived from… read more here.

Keywords: mitochondrial respiratory; thinned young; polysaccharide; apple ... See more keywords

Diminished force production and mitochondrial respiratory deficits are strain‐dependent myopathies of subacute limb ischemia

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recommendations! Published in 2017 at "Journal of Vascular Surgery"

DOI: 10.1016/j.jvs.2016.04.041

Abstract: Objective: Reduced skeletal muscle mitochondrial function might be a contributing mechanism to the myopathy and activity based limitations that typically plague patients with peripheral arterial disease (PAD). We hypothesized that mitochondrial dysfunction, myofiber atrophy, and… read more here.

Keywords: respiratory; muscle; mitochondrial respiratory; limb ischemia ... See more keywords