Cardiac mitochondrial structure and function in tafazzin-knockdown mice.
Sign Up to like & getrecommendations! Published in 2018 at "Mitochondrion"
DOI: 10.1016/j.mito.2018.10.005
Abstract: Mutations in the tafazzin gene are the basis of Barth syndrome. The tafazzin protein is responsible for the synthesis of cardiolipin. Doxycycline-induced tafazzin-knockdown mice have been used as a model for Barth syndrome. In the… read more here.
Keywords: tafazzin knockdown; knockdown mice; barth syndrome; cardiac mitochondrial ... See more keywords
Sericin-mediated improvement of dysmorphic cardiac mitochondria from hypercholesterolaemia is associated with maintaining mitochondrial dynamics, energy production, and mitochondrial structure
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2055088
Abstract: Abstract Context Sericin is a component protein in the silkworm cocoon [Bombyx mori Linnaeus (Bombycidae)] that improves dysmorphic cardiac mitochondria under hypercholesterolemic conditions. This is the first study to explore cardiac mitochondrial proteins associated with… read more here.
Keywords: energy production; cardiac mitochondria; mitochondria hypercholesterolaemia; mitochondrial structure ... See more keywords
Role of Constitutive STAR in Mitochondrial Structure and Function in MA-10 Leydig Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac091
Abstract: The steroidogenic acute regulatory protein (STAR) is critical for the transport of cholesterol into the mitochondria for hormone-induced steroidogenesis. Steroidogenic cells express STAR under control conditions (constitutive STAR). Upon hormonal stimulation, STAR localizes to the… read more here.
Keywords: structure function; star; mitochondrial structure; constitutive star ... See more keywords
Potential indicators of mitochondrial structure and function.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220520161200
Abstract: Mitochondria regulate a range of important physiological and biochemical cellular processes including apoptotic cell death, energy production, calcium homeostasis, oxidative stress, and lipid metabolism. Given their role as the 'engines' of cells, their dysfunction is… read more here.
Keywords: function; structure function; potential indicators; indicators mitochondrial ... See more keywords
The Functional Impact of Mitochondrial Structure Across Subcellular Scales
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.541040
Abstract: Mitochondria are key determinants of cellular health. However, the functional role of mitochondria varies from cell to cell depending on the relative demands for energy distribution, metabolite biosynthesis, and/or signaling. In order to support the… read more here.
Keywords: functional impact; energy; structure across; contact sites ... See more keywords
Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092564
Abstract: Simple Summary Mitochondria, which play crucial roles in energy production and in maintaining cellular homeostasis, are potential therapeutic targets in a variety of diseases including cancer. This review discusses methods to evaluate the structural and… read more here.
Keywords: function; changes mitochondrial; structure function; mitochondrial structure ... See more keywords
Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18081812
Abstract: Mitochondria supply cells with energy in the form of ATP, guide apoptosis, and contribute to calcium buffering and reactive oxygen species production. To support these diverse functions, mitochondria form an extensive network with smaller clusters… read more here.
Keywords: regulation mitochondrial; dynamics cytoskeleton; structure dynamics; mitochondrial structure ... See more keywords
Prenatal Low-Protein Diet Affects Mitochondrial Structure and Function in the Skeletal Muscle of Adult Female Offspring
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14061158
Abstract: Gestational low-protein (LP) diet leads to glucose intolerance and insulin resistance in adult offspring. We had earlier demonstrated that LP programming affects glucose disposal in females. Mitochondrial health is crucial for normal glucose metabolism in… read more here.
Keywords: function; structure function; mitochondrial structure; female offspring ... See more keywords