The Secret of the Kissing Cousins: an ER-mitochondrial tethering protein regulates Ca2+ crosstalk in mammalian neurons
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy020
Abstract: Commentary on ‘ER-mitochondria tethering by PDZD8 regulates Ca dynamics in mammalian neurons’ by Hirabayashi et al., Science 2017. In cardiomyocytes, large amounts of calcium (Ca2þ) are released from the sarcoplasmic reticulum (SR) into the cytosol… read more here.
Keywords: protein; secret kissing; kissing cousins; mitochondrial tethering ... See more keywords
The role of Mfn2 in the structure and function of ER-mitochondrial tethering in vivo.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.253443
Abstract: The mitochondria-ER contacts (MERCs) plays an essential role in multiple cell physiological process. While Mfn2 was the first protein implicated in the formation of MERCs, it is debated whether it acts as a tether or… read more here.
Keywords: mfn2; mfn2 structure; close contacts; mitochondrial tethering ... See more keywords