A simple and efficient toolset for analysing mitochondrial trafficking in neuronal cells.
Sign Up to like & getrecommendations! Published in 2018 at "Acta histochemica"
DOI: 10.1016/j.acthis.2018.09.001
Abstract: Mitochondria are crucial for cells, supplying up to 90% of the energy requirements for neurons. Their correct localisation is crucial and ensured by a transport system. Mitochondrial trafficking in neurons is particularly critical, because mitochondria… read more here.
Keywords: mitochondrial trafficking; neuronal cells; mitrakd; analysing mitochondrial ... See more keywords
The Interplay of Axonal Energy Homeostasis and Mitochondrial Trafficking and Anchoring.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2017.01.005
Abstract: Mitochondria are key cellular power plants essential for neuronal growth, survival, function, and regeneration after injury. Given their unique morphological features, neurons face exceptional challenges in maintaining energy homeostasis at distal synapses and growth cones… read more here.
Keywords: mitochondrial trafficking; energy; energy homeostasis; trafficking anchoring ... See more keywords
Alcohol, neuronal plasticity, and mitochondrial trafficking
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208744119
Abstract: Consumption of alcohol creates a sense of euphoria, reduces inhibition, and increases sociability and impulsivity (1). The age at which alcohol is first experienced is a key factor contributing to the likelihood to misuse alcohol… read more here.
Keywords: role; mitochondrial trafficking; brain; plasticity ... See more keywords
Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00109-19
Abstract: The Myc gene is a universal oncogene that promotes aggressive cancer, but its role in metastasis has remained elusive. Here, we show that Myc transcriptionally controls a gene network of subcellular mitochondrial trafficking that includes… read more here.
Keywords: metastasis; cell invasion; myc regulation; network ... See more keywords
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Reports"
DOI: 10.15252/embr.202052006
Abstract: Abstract Tunneling nanotubes (TNTs) are actinârich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs transport signaling molecules, vesicles, organelles, and even pathogens. However, the molecular mechanisms regulating… read more here.
Keywords: tunneling nanotubes; mitochondrial trafficking; modulates mitochondrial; mical2pv ... See more keywords