SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-19102-2
Abstract: Mitophagy, the selective degradation of mitochondria by autophagy, is crucial for the maintenance of healthy mitochondrial pool in cells. The critical event in mitophagy is the translocation of cytosolic Parkin, a ubiquitin ligase, to the… read more here.
Keywords: parkin translocation; mitochondrial translocation; translocation; sesn2 ... See more keywords
Platelet-derived respiratory-competent mitochondria transfer to mesenchymal stem cells to promote wound healing via metabolic reprogramming
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DOI: 10.1080/09537104.2021.1961717
Abstract: ABSTRACT Mitochondria regulate intracellular metabolism and are also involved in intercellular transfer in vitro and in vivo, thereby affecting the function of adjacent cells. Mitochondria can also be transferred to various differentiated cells to improve… read more here.
Keywords: wound healing; mitochondrial translocation; metabolic reprogramming; mesenchymal stem ... See more keywords
Molecular Mechanism Underlying Hypoxic Preconditioning-Promoted Mitochondrial Translocation of DJ-1 in Hypoxia/Reoxygenation H9c2 Cells
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DOI: 10.3390/molecules25010071
Abstract: DJ-1 was recently reported to be involved in the cardioprotection of hypoxic preconditioning (HPC) against hypoxia/reoxygenation (H/R)-induced oxidative stress damage, by preserving mitochondrial complex I activity and, subsequently, inhibiting mitochondrial reactive oxygen species (ROS) generation.… read more here.
Keywords: hypoxia reoxygenation; hypoxic preconditioning; mitochondrial translocation; translocation ... See more keywords