Alda-1 treatment promotes the therapeutic effect of mitochondrial transplantation for myocardial ischemia-reperfusion injury☆
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.12.024
Abstract: Mitochondrial damage is a critical driver in myocardial ischemia-reperfusion (I/R) injury and can be alleviated via the mitochondrial transplantation. The efficiency of mitochondrial transplantation is determined by mitochondrial vitality. Because aldehyde dehydrogenase 2 (ALDH2) has… read more here.
Keywords: mitochondrial transplantation; injury; transplantation; alda treatment ... See more keywords
Mitochondrial Transplantation for Organ Rescue.
Sign Up to like & getrecommendations! Published in 2022 at "Mitochondrion"
DOI: 10.1016/j.mito.2022.02.007
Abstract: Mitochondrial transplantation involves the replacement or augmentation of native mitochondria damaged, by ischemia, with viable, respiration-competent mitochondria isolated from non-ischemic tissue obtained from the patient's own body. The uptake and cellular functional integration of the… read more here.
Keywords: mitochondrial transplantation; transplantation; organ rescue; transplantation organ ... See more keywords
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells
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DOI: 10.1055/a-1967-2066
Abstract: Abstract Mitochondrial dysfunction is a basic mechanism leading to drug nephrotoxicity. Replacement of defective mitochondria with freshly isolated mitochondria is potentially a comprehensive tool to inhibit cytotoxicity induced by ifosfamide on renal proximal tubular cells… read more here.
Keywords: renal proximal; rptcs; rat; mitochondrial transplantation ... See more keywords
Mitochondrial Transplantation: A Unique Treatment Strategy.
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DOI: 10.1097/fjc.0000000000001247
Abstract: Mitochondrial transplantation refers to the process of introducing isolated mitochondria into a damaged area of the heart or other organs. In the past decade, this technique has been continuously updated as the fundamental research on… read more here.
Keywords: transplantation unique; mitochondrial transplantation; transplantation; treatment strategy ... See more keywords
Current progress of mitochondrial transplantation that promotes neuronal regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Translational Neurodegeneration"
DOI: 10.1186/s40035-019-0158-8
Abstract: BackgroundMitochondria are the major source of intracellular adenosine triphosphate (ATP) and play an essential role in a plethora of physiological functions, including the regulation of metabolism and the maintenance of cellular homeostasis. Mutations of mitochondrial… read more here.
Keywords: current progress; mitochondrial transplantation; regeneration; progress mitochondrial ... See more keywords
Mitochondrial transplantation: applications for pediatric patients with congenital heart disease.
Sign Up to like & getrecommendations! Published in 2018 at "Translational pediatrics"
DOI: 10.21037/tp.2018.02.02
Abstract: Mitochondrial transplantation refers to transplantation of respiratory competent mitochondria from healthy tissue into tissues injured by ischemia and reperfusion. This technique has been utilized for recovery of myocardial dysfunction in pediatric patients. The preclinical experience… read more here.
Keywords: mitochondrial transplantation; transplantation applications; applications pediatric; pediatric patients ... See more keywords
“Empowering” Cardiac Cells via Stem Cell Derived Mitochondrial Transplantation- Does Age Matter?
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DOI: 10.3390/ijms22041824
Abstract: With cardiovascular diseases affecting millions of patients, new treatment strategies are urgently needed. The use of stem cell based approaches has been investigated during the last decades and promising effects have been achieved. However, the… read more here.
Keywords: mitochondrial transplantation; stem; stem cells; stem cell ... See more keywords
Mitochondrial transplantation strategies as potential therapeutics for central nervous system trauma
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.226382
Abstract: Mitochondria are essential cellular organelles critical for generating adenosine triphosphate for cellular homeostasis, as well as various mechanisms that can lead to both necrosis and apoptosis. The field of “mitochondrial medicine” is emerging in which… read more here.
Keywords: mitochondrial transplantation; nervous system; central nervous; transplantation ... See more keywords
Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Immune Network"
DOI: 10.4110/in.2022.22.e14
Abstract: Osteoarthritis (OA) is a common degenerative joint disease characterized by breakdown of joint cartilage. Mitochondrial dysfunction of the chondrocyte is a risk factor for OA progression. We examined the therapeutic potential of mitochondrial transplantation for… read more here.
Keywords: progression; mitochondrial function; mitochondrial transplantation; transplantation ... See more keywords