Glutamine-Derived Aspartate Biosynthesis in Cancer Cells: Role of Mitochondrial Transporters and New Therapeutic Perspectives
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DOI: 10.3390/cancers14010245
Abstract: Simple Summary In recent years, aspartate has been increasingly acknowledged as a critical player in the metabolism of cancer cells which use this metabolite for nucleotide and protein synthesis and for redox homeostasis. Most intracellular… read more here.
Keywords: mitochondrial transporters; cancer; role; glutamine derived ... See more keywords
Role of Mitochondrial Transporters on Metabolic Rewiring of Pancreatic Adenocarcinoma: A Comprehensive Review
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DOI: 10.3390/cancers15020411
Abstract: Simple Summary Metabolic rewiring is now considered a hallmark of cancer. Pancreatic ductal adenocarcinoma (PDAC) extensively rewires its metabolism especially for the utilization of glucose and glutamine that are mainly used to provide the biosynthetic… read more here.
Keywords: mitochondrial transporters; role; review; metabolic rewiring ... See more keywords