Mitochondrial E3 ubiquitin ligase 1 (MUL1) as a novel therapeutic target for diseases associated with mitochondrial dysfunction
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DOI: 10.1002/iub.2657
Abstract: Mitochondrial E3 ubiquitin ligase 1 (MUL1) is a mitochondrial outer membrane‐anchored protein‐containing transmembrane domain in its N‐ and C‐terminal regions, where both are exposed to the cytosol. Interestingly the C‐terminal region has a RING finger… read more here.
Keywords: associated mitochondrial; ubiquitin ligase; mitochondrial ubiquitin; mul1 ... See more keywords
Mitochondrial E3 ubiquitin ligase MARCH5 is required for mouse oocyte meiotic maturation
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DOI: 10.1093/biolre/ioac215
Abstract: Abstract As the most abundant organelles in oocytes, mitochondria play an important role in maintaining oocyte quality. Here, we report that March5, encoding a mitochondrial ubiquitin ligase that promotes mitochondrial elongation, plays a critical role… read more here.
Keywords: maturation; meiotic maturation; mitochondrial ubiquitin; oocyte meiotic ... See more keywords