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Published in 2020 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2020.03.001
Abstract: Eukaryotic cells must accurately monitor the integrity of the mitochondrial network to overcome environmental insults and respond to physiological cues. The mitochondrial unfolded protein response (UPRmt) is a mitochondrial-to-nuclear signaling pathway that maintains mitochondrial proteostasis,…
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Keywords:
response;
mitochondrial upr;
integrated stress;
stress response ... See more keywords
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Published in 2019 at "Journal of Cell Science"
DOI: 10.1242/jcs.223891
Abstract: ABSTRACT The Fe(II) and 2-oxoglutarate-dependent oxygenase Alkb homologue 1 (Alkbh1) has been shown to act on a wide range of substrates, like DNA, tRNA and histones. Thereby different enzymatic activities have been identified including, among…
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Keywords:
alkbh1;
mitochondrial upr;
knockdown induces;
microscopy ... See more keywords