Protective effect of mitochondrially targeted antioxidant MitoQ on oxidatively stressed fibroblasts
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DOI: 10.1007/s11696-017-0359-5
Abstract: Abstract3T3 and VH10 cells were subjected to oxidative damage by hydroxyl radicals generated from Cu(II) ions and ascorbate. The presence of reactive oxygen and nitrogen species in cells was determined using fluorescent dyes. MitoQ—a mitochondrially… read more here.
Keywords: effect mitochondrially; mitochondrially targeted; protective effect; antioxidant mitoq ... See more keywords
Mitochondrially targeted tamoxifen alleviates markers of obesity and type 2 diabetes mellitus in mice
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DOI: 10.1038/s41467-022-29486-z
Abstract: Type 2 diabetes mellitus represents a major health problem with increasing prevalence worldwide. Limited efficacy of current therapies has prompted a search for novel therapeutic options. Here we show that treatment of pre-diabetic mice with… read more here.
Keywords: senescent; type diabetes; mitochondrially targeted; diabetes mellitus ... See more keywords
Mitochondrially targeted proximity biotinylation and proteomic analysis in Plasmodium falciparum
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DOI: 10.1101/2022.05.30.494025
Abstract: Despite ongoing efforts to control malaria infection, progress in lowering the number of deaths and infections appears to have stalled. The continued high incidence of malaria infection and mortality is in part due to emergence… read more here.
Keywords: plasmodium falciparum; proximity biotinylation; mitochondrially targeted; falciparum ... See more keywords