Susceptibility of Mitophagy‐Deficient Tumors to Ferroptosis Induction by Relieving the Suppression of Lipid Peroxidation
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202412593
Abstract: The identification of ferroptosis‐sensitive cancers is critical for the application of ferroptosis‐inducing therapies in cancer therapy. Here, patient‐derived organoid screening models of colorectal cancer are established to identify tumors that are sensitive to ferroptosis‐inducing therapy.… read more here.
Keywords: mitophagy deficient; ferroptosis; deficient tumors; lipid peroxidation ... See more keywords
Mitophagy in Yeast: A Screen of Mitophagy-Deficient Mutants.
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DOI: 10.1007/7651_2017_13
Abstract: Mitochondrial autophagy (mitophagy) is a process that selectively degrades mitochondria via autophagy. Recent studies have shown that mitophagy plays an important role in mitochondrial homeostasis by degrading damaged or excess mitochondria. The budding yeast Saccharomyces… read more here.
Keywords: yeast screen; mitophagy yeast; deficient mutants; mitophagy deficient ... See more keywords