Emerging role of mitophagy in heart failure: from molecular mechanism to targeted therapy
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DOI: 10.1080/15384101.2023.2167949
Abstract: ABSTRACT Heart failure is defined as a drop in heart’s pump function, accounting for reduced blood output and venous stasis, and constitutes the end stage of various cardiovascular diseases. Although mild mitochondrial dysfunction may hinder… read more here.
Keywords: mitophagy heart; heart failure; emerging role; heart ... See more keywords
The Role of Alternative Mitophagy in Heart Disease
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DOI: 10.3390/ijms24076362
Abstract: Autophagy is essential for maintaining cellular homeostasis through bulk degradation of subcellular constituents, including misfolded proteins and dysfunctional organelles. It is generally governed by the proteins Atg5 and Atg7, which are critical regulators of the… read more here.
Keywords: role alternative; alternative mitophagy; heart; mitophagy heart ... See more keywords