Leptin Maintained Zinc Homeostasis Against Glutamate-Induced Excitotoxicity by Preventing Mitophagy-Mediated Mitochondrial Activation in HT22 Hippocampal Neuronal Cells
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DOI: 10.3389/fneur.2018.00322
Abstract: Developmental seizure-induced long-term neuronal hyperexcitation is partially mediated by regenerative mossy fiber sprouting in hippocampus. Yet, there are no effective drugs available to block this pathological process. Recently, leptin has been shown to prevent the… read more here.
Keywords: mitophagy mediated; glutamate induced; leptin; zinc homeostasis ... See more keywords