Mitophagy in neurodegeneration and aging
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2017.02.007
Abstract: &NA; Mitochondrial dysfunction contributes to normal aging and a wide spectrum of age‐related diseases, including neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. It is important to maintain a healthy mitochondrial population which is… read more here.
Keywords: neurodegeneration aging; mitophagy; mitophagy neurodegeneration;
Mitophagy and Neurodegeneration: Between the Knowns and the Unknowns
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.837337
Abstract: Macroautophagy (henceforth autophagy) an evolutionary conserved intracellular pathway, involves lysosomal degradation of damaged and superfluous cytosolic contents to maintain cellular homeostasis. While autophagy was initially perceived as a bulk degradation process, a surfeit of studies… read more here.
Keywords: knowns unknowns; neurodegeneration knowns; mitophagy neurodegeneration; degradation ... See more keywords