Selective elimination of senescent cells by mitochondrial targeting is regulated via ANT2
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.382
Abstract: Cellular senescence is stable cell cycle arrest limiting proliferative potential of cells. Inability of immune cells to eliminate senescent cells from the organism may lead to development of age-related diseases. We have developed several mitocans,… read more here.
Keywords: mitotam; senescent cells; elimination senescent; selective elimination ... See more keywords
Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00727-22
Abstract: Many of the currently available anti-parasitic and anti-fungal frontline drugs have severe limitations, including adverse side effects, complex administration, and increasing occurrence of resistance. The discovery and development of new therapeutic agents is a costly… read more here.
Keywords: mitotam; anti cancer; cancer drug; drug candidate ... See more keywords