Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches
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DOI: 10.18632/oncotarget.18968
Abstract: Mitotane (o,p’DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches… read more here.
Keywords: lipidomic approaches; mitotane; mitochondria associated; mitotane induced ... See more keywords