Spironolactone is associated with reduced mitotane levels in adrenocortical carcinoma patients.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine-related cancer"
DOI: 10.1530/erc-21-0202
Abstract: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a poor prognosis. Mitotane, a derivative of the pesticide DDT, has been used successfully as first line chemotherapy since the 1960s, if maintained within a narrow… read more here.
Keywords: spl; mitotane levels; spironolactone; mitotane ... See more keywords