Synthesis and anti-mitotic activity of 2,4- or 2,6-disubstituted- and 2,4,6-trisubstituted-2H-pyrazolo[4,3-c]pyridines.
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DOI: 10.1016/j.ejmech.2018.03.037
Abstract: An efficient synthetic route for the synthesis of 2H-pyrazolo[4,3-c]pyridines, primarily varying by the substituents at the 2-, 4- and 6-positions, is described here. A Sonogashira-type cross-coupling reaction was employed to yield 3-alkynyl-1H-pyrazole-4-carbaldehydes, ethanones and propanones… read more here.
Keywords: anti mitotic; pyrazolo pyridines; synthesis anti; mitotic activity ... See more keywords
A case of melanocytic matricoma with prominent mitotic activity and melanocytic hyperplasia
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DOI: 10.1111/ijd.14109
Abstract: and in-line with SEER analysis, we find radiotherapy use to be associated with worse survival outcomes in EMPD patients. As previously suggested, radiation treatment benefit may be reduced due to lack of standardized guidelines for… read more here.
Keywords: melanocytic matricoma; use; matricoma prominent; prominent mitotic ... See more keywords
Analysis of Tumor Proliferation Markers in Early-Stage Luminal Breast Cancer: A Comprehensive Study Using Mitotic Activity Index, Ki-67, and Phosphohistone H3 Expression
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DOI: 10.1177/10668969241295355
Abstract: Introduction and Aim: Routinely used proliferation markers such as mitotic activity index (MAI) and Ki-67 index show limited reproducibility due to high interobserver variability in breast cancer assessment. Phosphohistone H3 (PhH3), a novel proliferation marker,… read more here.
Keywords: breast cancer; mitotic activity; proliferation; index ... See more keywords
Chromosomal Disturbances during Mitotic Activity of Root Tip Cells in Allium by Certain Commonly Used Antibiotics
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DOI: 10.5530/pj.2018.2.60
Abstract: Introduction: The certain commonly used antibiotics (cefixime, metronidazole, ciprofloxacin, cefpodoxime and cetirizine) purchased from the chemist shop in Mokokchung town, Nagaland and effects on mitotic activity of root tip meristematic cells of Allium Cepa were… read more here.
Keywords: cells allium; mitotic activity; activity root; root tip ... See more keywords