Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01876-8
Abstract: The Polo kinase is a master regulator of mitosis and cytokinesis conserved from yeasts to humans. Polo is composed of an N-term kinase domain (KD) and a C-term polo-box domain (PBD), which regulates its subcellular… read more here.
Keywords: kinase; activation; entry; mitotic entry ... See more keywords
CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry.
Sign Up to like & getrecommendations! Published in 2022 at "Nature cell biology"
DOI: 10.1038/s41556-022-00886-z
Abstract: The disassembly of integrin-containing focal adhesions (FAs) at mitotic entry is essential for cell rounding, mitotic retraction fibre formation, bipolar spindle positioning and chromosome segregation. The mechanism that drives FA disassembly at mitotic entry is… read more here.
Keywords: entry; kindlin degradation; disassembly mitotic; mitotic entry ... See more keywords
Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8090933
Abstract: Inositol pyrophosphates (IPPs) comprise a specific class of signaling molecules that regulate central biological processes in eukaryotes. The conserved Vip1/PPIP5K family controls intracellular IP8 levels, the highest phosphorylated form of IPPs present in yeasts, as… read more here.
Keywords: ip8; kinetochore architecture; pombe; mitotic entry ... See more keywords