Regulation of Mitotic Exit in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6502-1_1
Abstract: The Mitotic Exit Network (MEN) is an essential signaling pathway, closely related to the Hippo pathway in mammals, which promotes mitotic exit and initiates cytokinesis in the budding yeast Saccharomyces cerevisiae. Here, we summarize the… read more here.
Keywords: saccharomyces cerevisiae; mitotic exit; regulation mitotic; exit ... See more keywords
Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20
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DOI: 10.1038/s41589-020-0495-z
Abstract: The anaphase-promoting complex/cyclosome (APC/C) is a ubiquitin ligase that initiates anaphase and mitotic exit. APC/C is activated by Cdc20 and inhibited by the mitotic checkpoint complex (MCC), which delays mitotic exit when the spindle assembly… read more here.
Keywords: small molecule; mitosis; mitotic exit; apc ... See more keywords
Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network
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DOI: 10.1091/mbc.e19-10-0584
Abstract: The Mitotic Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, translates nuclear position into a signal to exit from mitosis. Here we describe how scaffolding the MEN onto spindle pole bodies (SPB—centrosome equivalent)… read more here.
Keywords: exit; mitotic exit; exit network; mitosis ... See more keywords
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit
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DOI: 10.1242/bio.059565
Abstract: ABSTRACT Spc110 is an essential component of the spindle pole body (SPB), the yeast equivalent of the centrosome, that recruits the γ-tubulin complex to the nuclear side of the SPB to produce the microtubules that… read more here.
Keywords: mitotic exit; cycle progression; cell cycle; component ... See more keywords
AURKA destruction is decoupled from its activity at mitotic exit but essential to suppress interphase activity.
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DOI: 10.1242/jcs.243071
Abstract: Activity of AURKA is controlled through multiple mechanisms including phosphorylation, ubiquitin-mediated degradation, and allosteric interaction with TPX2. Activity peaks at mitosis before AURKA is degraded during and after mitotic exit in a process strictly dependent… read more here.
Keywords: mitotic exit; interphase; destruction; aurka ... See more keywords
Balancing of the mitotic exit network and cell wall integrity signaling governs the development and pathogenicity in Magnaporthe oryzae
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DOI: 10.1371/journal.ppat.1009080
Abstract: The fungal cell wall plays an essential role in maintaining cell morphology, transmitting external signals, controlling cell growth, and even virulence. Relaxation and irreversible stretching of the cell wall are the prerequisites of cell division… read more here.
Keywords: mitotic exit; cell division; cell wall; cell ... See more keywords
A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit
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DOI: 10.15698/mic2018.08.644
Abstract: The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells. Cell cycle events are ordered by synthesis and… read more here.
Keywords: budding yeast; mitotic exit; substrate phosphorylation; phosphorylation dephosphorylation ... See more keywords
Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae
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DOI: 10.3390/genes11020195
Abstract: In order to preserve genome integrity and their ploidy, cells must ensure that the duplicated genome has been faithfully replicated and evenly distributed before they complete their division by mitosis. To this end, cells have… read more here.
Keywords: cycle checkpoints; saccharomyces cerevisiae; mitotic exit; cell cycle ... See more keywords