EMT‐Induced Cell‐Mechanical Changes Enhance Mitotic Rounding Strength
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DOI: 10.1002/advs.202001276
Abstract: Abstract To undergo mitosis successfully, most animal cells need to acquire a round shape to provide space for the mitotic spindle. This mitotic rounding relies on mechanical deformation of surrounding tissue and is driven by… read more here.
Keywords: mechanical changes; emt; emt induced; mitotic rounding ... See more keywords
Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding
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DOI: 10.1038/s41467-017-01147-6
Abstract: To divide, most animal cells drastically change shape and round up against extracellular confinement. Mitotic cells facilitate this process by generating intracellular pressure, which the contractile actomyosin cortex directs into shape. Here, we introduce a… read more here.
Keywords: genes involved; genome scale; mechanical phenotyping; mitotic rounding ... See more keywords