Development and validation of ELISA for screening of Kratom (Mitragyna speciosa) habitual users using urinary AZ122 biomarker
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2392
Abstract: Kratom (Mitragyna speciosa Korth) has been used traditionally in Southeast Asia for its therapeutic properties. The major alkaloid of kratom, mitragynine, binds to opioid receptors to give opioid‐like effects that causes addiction. In our previous… read more here.
Keywords: mitragyna speciosa; biomarker; kratom; habitual users ... See more keywords
Chemical constituents and nitric oxide inhibitory activity of supercritical carbon dioxide extracts from Mitragyna speciosa leaves
Sign Up to like & getrecommendations! Published in 2019 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2016.09.005
Abstract: Abstract Mitragyna speciosa Korth., is a controversial plant that possesses various medicinal values and has been used from time immemorial in folk medicine. Recently, it has been widely abused as a narcotic source. The aim… read more here.
Keywords: inhibitory activity; mitragyna speciosa; speciosa leaves;
The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c00257
Abstract: Two separate commercial products of kratom [Mitragyna speciosa (Korth.) Havil. Rubiaceae] were used to generate reference standards of its indole and oxindole alkaloids. While kratom has been studied for over a century, the characterization data… read more here.
Keywords: indole oxindole; oxindole alkaloids; mitragyna speciosa; chemistry ... See more keywords
Metabolite and Molecular Characterization of Mitragyna speciosa Identifies Developmental and Genotypic Effects on Monoterpene Indole and Oxindole Alkaloid Composition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.3c00092
Abstract: The monoterpene indole alkaloid (MIA) mitragynine has garnered attention as a potential treatment for pain, opioid use disorder, and opioid withdrawal because of its combined pharmacology at opioid and adrenergic receptors in humans. This alkaloid… read more here.
Keywords: mitragyna speciosa; speciosa; mitragyna; mitragynine ... See more keywords
Characterization of urinary protein profile in regular kratom (Mitragyna speciosa korth.) users in Malaysia.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of addictive diseases"
DOI: 10.1080/10550887.2021.1981122
Abstract: Mitragyna speciosa (Korth.) also known as kratom or ketum has been traditionally used for its diverse medicinal value in Southeast Asia. Despite of its therapeutic value, kratom's safety profile remains deficiently elucidated. Our study aims… read more here.
Keywords: protein; kratom; urinary protein; kratom users ... See more keywords
The Use of Kratom (Mitragyna speciosa Korth.) Among People Who Co-use Heroin and Methamphetamine in Malaysia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Addiction Medicine"
DOI: 10.1097/adm.0000000000000876
Abstract: Objectives: Kratom (Mitragyna speciosa Korth.), an indigenous medicinal plant, has been widely used as a traditional remedy in Southeast Asia. However, its combined consumption with other substances has received scarce attention. This study investigates the… read more here.
Keywords: mitragyna speciosa; kratom mitragyna; heroin methamphetamine; kratom ... See more keywords
Kratom (Mitragyna speciosa): worldwide issues.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Psychiatry"
DOI: 10.1097/yco.0000000000000621
Abstract: PURPOSE OF REVIEW To inform readers about the increasingly popular Western dietary supplement, kratom (Mitragyna speciosa) and how the products are available in the Western world compared with traditional Southeast Asian use. Kratom has been… read more here.
Keywords: mitragyna speciosa; kratom mitragyna; western world; speciosa worldwide ... See more keywords
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine
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DOI: 10.1111/adb.12639
Abstract: Kratom, derived from the plant Mitragyna speciosa, is receiving increased attention as an alternative to traditional opiates and as a replacement therapy for opiate dependence. Mitragynine (MG) and 7‐hydroxymitragynine (7‐HMG) are major psychoactive constituents of… read more here.
Keywords: self administration; intake; mitragyna speciosa; hmg ... See more keywords
Anorectic Effect, Biochemical and Hematological Profiles of Alkaloid Extract from Mitragyna speciosa Korth. in Rats
Sign Up to like & getrecommendations! Published in 2021 at "Sains Malaysiana"
DOI: 10.17576/jsm-2021-5003-19
Abstract: There is an on-going debate about medicinal use of kratom plant (Mitragyna speciosa (MS)) on whether it has beneficial or adverse effects. This study aimed to examine long-term weight-reducing effects, toxicity, and dopamine pathway activation… read more here.
Keywords: mitragyna speciosa; biochemical hematological; treatment; alkaloid extract ... See more keywords
Antinociceptive Activity of Aqueous Fraction of Kratom Leaves Mitragyna speciosa Korth.) on Male Swiss Albino Mice
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Organ Transplantation"
DOI: 10.22146/mot.32085
Abstract: Kratom (Mitragyna speciosa Korth.) has been known to have an analgesic opioid effect (antinociceptive). The major compound of kratom leaf is mitraginin, which has strong affinity on opioid receptor. The aim of this research is… read more here.
Keywords: kratom; mitragyna speciosa; fraction kratom; aqueous fraction ... See more keywords
Assessment of Cardiovascular Functioning Among Regular Kratom (Mitragyna speciosa Korth) Users: A Case Series
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.723567
Abstract: Multiorgan toxicities have been extensively reported in kratom (Mitragyna speciosa Korth) users in Western countries but not in Southeast Asia. Existing literature argued that this discrepancy may be due to underreporting of kratom-related toxicity cases… read more here.
Keywords: kratom; korth users; mitragyna speciosa; regular kratom ... See more keywords