Treatment of CD19‐positive mixed phenotype acute leukemia with blinatumomab
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25317
Abstract: sion rates following hospitalization for pediatric sickle cell crisis at freestanding children's hospitals: risk factors and hospital variation. Pediatr Blood Cancer. 2012;58:61-65. 4. Brodsky MA, Rodeghier M, Sanger M, et al. Risk Factors for 30-Day… read more here.
Keywords: mixed phenotype; cd19 positive; positive mixed; treatment cd19 ... See more keywords
Therapy for children and adults with mixed phenotype acute leukemia: a systematic review and meta-analysis
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DOI: 10.1038/s41375-018-0058-4
Abstract: The rarity of mixed-phenotype acute leukemia (MPAL) has resulted in diffuse literature consisting of small case series, thus precluding a consensus treatment approach. We conducted a meta-analysis and systematic review to investigate the association of… read more here.
Keywords: acute; analysis; mixed phenotype; meta ... See more keywords
The genomic and biological complexity of mixed phenotype acute leukemia
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DOI: 10.1080/10408363.2020.1829537
Abstract: Abstract Mixed phenotype acute leukemia (MPAL) is a heterogeneous group of leukemias that are defined immunophenotypically by antigen expression on blasts of both myeloid and lymphoid lineage. With the exception of BCR-ABL positive and KMT2A… read more here.
Keywords: phenotype acute; acute leukemia; leukemia; mixed phenotype ... See more keywords
B-Cell/Mixed Phenotype Acute Leukemia Following Lenalidomide Maintenance For Multiple Myeloma: A Study Of Two Cases
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqaa161.334
Abstract: The incidence of patients with multiple myeloma (MM) followed by hematologic malignancies as second primary malignancy is around 0.8 – 3.1%. The majority of cases are myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), however,… read more here.
Keywords: multiple myeloma; leukemia; lenalidomide maintenance; mixed phenotype ... See more keywords
Phlegmonous gastritis in a patient with mixed-phenotype acute leukemia in the neutropenia phase during chemotherapy
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DOI: 10.1097/md.0000000000017777
Abstract: Abstract Rationale: Phlegmonous gastritis is a rare bacterial infection of the gastric wall with high mortality. However, diagnosis of phlegmonous gastritis is difficult and standard treatment remains unestablished. Patient concerns: We report a 33-year-old male… read more here.
Keywords: chemotherapy; phlegmonous gastritis; mixed phenotype; patient mixed ... See more keywords
Adult mixed phenotype acute leukemia (MPAL): B/myeloid MPALisoMPO is distinct from other MPAL subtypes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13988
Abstract: Myeloperoxidase (MPO) is considered a specific marker of myeloid/non‐monocytic lineage in the diagnosis of mixed phenotype acute leukemia (MPAL). However, the clinical significance of isolated dim MPO expression in otherwise typical B lymphoblastic leukemia (B‐ALL;… read more here.
Keywords: mixed phenotype; phenotype acute; leukemia; acute leukemia ... See more keywords
The Clinical Tumor Lysis Syndrome in a Patient with Mixed Phenotype Acute Leukemia Undergoing Induction with Venetoclax and Azacitidine: A Case Report
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DOI: 10.1159/000524182
Abstract: A combination of azacitidine and venetoclax (AZA-VEN) has been approved for the treatment of adult treatment-naïve acute myeloid leukemia (AML) patients, ineligible for intensive chemotherapy. The protocol may also constitute an alternative for the treatment… read more here.
Keywords: mixed phenotype; phenotype acute; leukemia; patient ... See more keywords
Characteristics, Treatment Complexity, and Outcome of Mixed-Phenotype Acute Leukemia in Children in a Low–Middle-Income Country
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.941885
Abstract: Background Mixed-phenotype acute leukemia (MPAL) in children is an uncommon subtype of acute leukemia that cannot be definitively assigned to a specific lineage. There is no consensus on the best approach to therapy. Management is… read more here.
Keywords: flt3; mixed phenotype; year; acute ... See more keywords
Genomic Landscape of Mixed-Phenotype Acute Leukemia
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DOI: 10.3390/ijms231911259
Abstract: Mixed-phenotype leukemia (MPAL) is a type of acute leukemia in which the blast population shows mixed features of myeloid, T-lymphoid, and/or B-lymphoid differentiation. MPALs are rare and carry a poor prognosis, thus, often pose both… read more here.
Keywords: mixed phenotype; acute; genomic landscape; leukemia ... See more keywords
Recognizing Minor Leukemic Populations with Monocytic Features in Mixed-Phenotype Acute Leukemia by Flow Cell Sorting Followed by Cytogenetic and Molecular Studies: Report of Five Exemplary Cases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065260
Abstract: Mixed-phenotype acute leukemia (MPAL), a rare and heterogeneous category of acute leukemia, is characterized by cross-lineage antigen expression. Leukemic blasts in MPAL can be represented either by one population with multiple markers of different lineages… read more here.
Keywords: mixed phenotype; leukemic populations; acute leukemia; phenotype acute ... See more keywords
Mixed-phenotype acute leukemia: state-of-the-art of the diagnosis, classification and treatment.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia"
DOI: 10.5507/bp.2017.013
Abstract: Mixed-phenotype acute leukemia (MPAL) is a heterogeneous group of hematopoietic malignancies in which blasts show markers of multiple developmental lineages and cannot be clearly classified as acute myeloid or lymphoblastic leukemias. Historically, various names and… read more here.
Keywords: classification; treatment; mixed phenotype; acute leukemia ... See more keywords