Trehalose alleviates the phenotype of Machado–Joseph disease mouse models
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DOI: 10.1186/s12967-020-02302-2
Abstract: Background Machado–Joseph disease (MJD), also known as spinocerebellar ataxia type 3, is the most common of the dominantly inherited ataxias worldwide and is characterized by mutant ataxin-3 aggregation and neuronal degeneration. There is no treatment… read more here.
Keywords: mjd; machado joseph; disease; joseph disease ... See more keywords
‘Staying strong on the inside and outside’ to keep walking and moving around: Perspectives from Aboriginal people with Machado Joseph Disease and their families from the Groote Eylandt Archipelago, Australia
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DOI: 10.1371/journal.pone.0212953
Abstract: Machado Joseph Disease (MJD) (spinocerebellar ataxia 3) is a hereditary neurodegenerative disease causing progressive ataxia and loss of mobility. It is the most common spinocerebellar ataxia worldwide. Among Aboriginal families of Groote Eylandt and related… read more here.
Keywords: mjd; keep walking; walking moving; groote eylandt ... See more keywords