Identification of the GlialCAM interactome: the G protein-coupled receptors GPRC5B and GPR37L1 modulate megalencephalic leukoencephalopathy proteins
Sign Up to like & getrecommendations! Published in 2021 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddab155
Abstract: Abstract Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a type of vacuolating leukodystrophy, which is mainly caused by mutations in MLC1 or GLIALCAM. The two MLC-causing genes encode for membrane proteins of yet unknown function… read more here.
Keywords: megalencephalic leukoencephalopathy; mlc proteins; glialcam interactome; protein coupled ... See more keywords
GPR37 Receptors and Megalencephalic Leukoencephalopathy with Subcortical Cysts
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105528
Abstract: Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of vacuolating leukodystrophy (white matter disorder), which is mainly caused by defects in MLC1 or glial cell adhesion molecule (GlialCAM) proteins. In addition, autoantibodies to… read more here.
Keywords: subcortical cysts; leukoencephalopathy subcortical; receptors megalencephalic; megalencephalic leukoencephalopathy ... See more keywords