Synthetic lethal connectivity and graph transformer improve synthetic lethality prediction
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DOI: 10.1093/bib/bbae425
Abstract: Abstract Synthetic lethality (SL) has shown great promise for the discovery of novel targets in cancer. CRISPR double-knockout (CDKO) technologies can only screen several hundred genes and their combinations, but not genome-wide. Therefore, good SL… read more here.
Keywords: synthetic lethality; mlec isl; prediction; connectivity ... See more keywords