Reduced microRNA‐188‐3p expression contributes to apoptosis of spermatogenic cells in patients with azoospermia
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DOI: 10.1111/cpr.12297
Abstract: Human mutL homologl (MLH1) works coordinately in sequential steps to initiate repair of DNA mismatches, and aberrant MLH1 expression is related to spermatogenetic malfunction. In the present study, MLH1 expression in patients with azoospermia was… read more here.
Keywords: mlh1 expression; patients azoospermia; microrna 188; expression ... See more keywords
Disruption of a −35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells
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DOI: 10.1158/1078-0432.ccr-17-3678
Abstract: Purpose: MLH1 is a major tumor suppressor gene involved in the pathogenesis of Lynch syndrome and various sporadic cancers. Despite their potential pathogenic importance, genomic regions capable of regulating MLH1 expression over long distances have… read more here.
Keywords: colorectal cells; mlh1 expression; expression; ctcf ... See more keywords